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Effectiveness of Micronized Purified Flavonoid Fraction on Quality of Life in Patients with Chronic Venous Disease: A Systematic Review and Meta-analysis.

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Title: Effectiveness of Micronized Purified Flavonoid Fraction on Quality of Life in Patients with Chronic Venous Disease: A Systematic Review and Meta-analysis.
Authors: Santiago FR; Federal University of Goiás, Rua 5 n 243 Goiânia, Goiás, CEP-74115060, Brazil. fsan09@ufg.br., Celovska D; 1st Department of Internal Medicine, Medical Faculty, Comenius University and University Hospital, Bratislava, Slovakia., Thomis S; Department of Vascular Surgery, Centre for Lymphedema, UZ Leuven-University Hospitals Leuven, Leuven, Belgium., Blanc-Guillemaud V; Servier Medical Affairs, Suresnes, France., Onselaer MB; Soladis Clinical Studies, Roubaix, France., Serifou S; Soladis, Lyon, France., Yaltirik HP; Servier Medical Affairs, Suresnes, France., Bokuchava M; N. Bokhua Memorial Cardiovascular Center, Tbilisi State Medical University, Tbilisi, Georgia.
Source: Clinical drug investigation [Clin Drug Investig] 2026 Aug; Vol. 46 (8), pp. 809-825. Date of Electronic Publication: 2026 May 29.
Publication Type: Journal Article; Systematic Review; Meta-Analysis
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9504817 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1918 (Electronic) Linking ISSN: 11732563 NLM ISO Abbreviation: Clin Drug Investig Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effectiveness of Micronized Purified Flavonoid Fraction on Quality of Life in Patients with Chronic Venous Disease: A Systematic Review and Meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Santiago+FR%22">Santiago FR</searchLink>; Federal University of Goiás, Rua 5 n 243 Goiânia, Goiás, CEP-74115060, Brazil. fsan09@ufg.br.<br /><searchLink fieldCode="AU" term="%22Celovska+D%22">Celovska D</searchLink>; 1st Department of Internal Medicine, Medical Faculty, Comenius University and University Hospital, Bratislava, Slovakia.<br /><searchLink fieldCode="AU" term="%22Thomis+S%22">Thomis S</searchLink>; Department of Vascular Surgery, Centre for Lymphedema, UZ Leuven-University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Blanc-Guillemaud+V%22">Blanc-Guillemaud V</searchLink>; Servier Medical Affairs, Suresnes, France.<br /><searchLink fieldCode="AU" term="%22Onselaer+MB%22">Onselaer MB</searchLink>; Soladis Clinical Studies, Roubaix, France.<br /><searchLink fieldCode="AU" term="%22Serifou+S%22">Serifou S</searchLink>; Soladis, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Yaltirik+HP%22">Yaltirik HP</searchLink>; Servier Medical Affairs, Suresnes, France.<br /><searchLink fieldCode="AU" term="%22Bokuchava+M%22">Bokuchava M</searchLink>; N. Bokhua Memorial Cardiovascular Center, Tbilisi State Medical University, Tbilisi, Georgia.
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  Data: <searchLink fieldCode="JN" term="%229504817%22">Clinical drug investigation</searchLink> [Clin Drug Investig] 2026 Aug; Vol. 46 (8), pp. 809-825. <i>Date of Electronic Publication: </i>2026 May 29.
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        Value: 10.1007/s40261-026-01563-x
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      – TitleFull: Effectiveness of Micronized Purified Flavonoid Fraction on Quality of Life in Patients with Chronic Venous Disease: A Systematic Review and Meta-analysis.
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              Text: 2026 Aug
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              Y: 2026
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