Type II tRNA cleavage by SLFN14 endoribonuclease variants linked to inherited thrombocytopenia drives global translational repression.

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Title: Type II tRNA cleavage by SLFN14 endoribonuclease variants linked to inherited thrombocytopenia drives global translational repression.
Authors: Ding C; Department of Microbiology, Immunology‌‌ and Molecular Genetics, Joe R. & Teresa Lozano Long School of Medicine, The University of Texas at San Antonio, San Antonio, Texas, New York, United States of America.; Department of Infectious Disease, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China., Liu XA; Division of Nutritional Sciences, Cornell University, Texas, New York, United States of America., Zhang F; Department of Microbiology, Immunology‌‌ and Molecular Genetics, Joe R. & Teresa Lozano Long School of Medicine, The University of Texas at San Antonio, San Antonio, Texas, New York, United States of America., Uematsu S; Division of Nutritional Sciences, Cornell University, Texas, New York, United States of America., Qian SB; Division of Nutritional Sciences, Cornell University, Texas, New York, United States of America., Xiang Y; Department of Microbiology, Immunology‌‌ and Molecular Genetics, Joe R. & Teresa Lozano Long School of Medicine, The University of Texas at San Antonio, San Antonio, Texas, New York, United States of America.
Source: PLoS biology [PLoS Biol] 2026 May 29; Vol. 24 (5), pp. e3003830. Date of Electronic Publication: 2026 May 29 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1545-7885
DOI:10.1371/journal.pbio.3003830