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3-Nitropropionic Acid-Induced Huntington's Disease in Preclinical Models: Mechanisms, Peripheral Toxicities, Model Gaps, and Future Directions.

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Title: 3-Nitropropionic Acid-Induced Huntington's Disease in Preclinical Models: Mechanisms, Peripheral Toxicities, Model Gaps, and Future Directions.
Authors: Dontiboina HR; KL College of Pharmacy, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, Andhra Pradesh, India, 522302., Yadava S; KL College of Pharmacy, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, Andhra Pradesh, India, 522302., Nakka VP; Department of Systems and Computational Biology, School of Life Sciences, University of Hyderabad, Hyderabad, 500046, India., Dumala N; KL College of Pharmacy, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, Andhra Pradesh, India, 522302., Viswanadh MK; KL College of Pharmacy, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, Andhra Pradesh, India, 522302., Guntupalli C; KL College of Pharmacy, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, Andhra Pradesh, India, 522302., Nalluri BN; KL College of Pharmacy, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, Andhra Pradesh, India, 522302., Malothu N; KL College of Pharmacy, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, Andhra Pradesh, India, 522302., Yadagiri G; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Kolkata, 700 054, India., Gujjari L; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA., Ramakrishna K; KL College of Pharmacy, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, Andhra Pradesh, India, 522302. kakarlaramakrishna@kluniversity.in.
Source: Molecular neurobiology [Mol Neurobiol] 2026 May 30; Vol. 63 (1). Date of Electronic Publication: 2026 May 30.
Publication Type: Journal Article; Review
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1559-1182
DOI:10.1007/s12035-026-05967-w