Novel Long-Acting Ghrelin Analogue PEP-064 Restores Energy Balance in C26 and Lewis Lung Carcinoma-Induced cachexia in Mice.

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Title: Novel Long-Acting Ghrelin Analogue PEP-064 Restores Energy Balance in C26 and Lewis Lung Carcinoma-Induced cachexia in Mice.
Authors: Hunt JE; Pephexia Therapeutics ApS, Frederiksberg, Denmark., Lund C; Pephexia Therapeutics ApS, Frederiksberg, Denmark., Chen B; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut, USA., Diaz AR; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut, USA., Dmytriyeva O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Marcotorchino J; Biomeostasis, La Penne sur Huveaune, France., Löbner K; Faculty of Life Sciences, Leipzig University, Leipzig, Germany., Mörl K; Faculty of Life Sciences, Leipzig University, Leipzig, Germany., Andersen NR; Department of Biomedical Sciences, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark., Ogueboule ZKJ; Department of Biomedical Sciences, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark., Frank E; Department of Biomedical Sciences, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark., Stöhr J; Apigenex sro, Prague, Czech Republic., Meseguer D; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut, USA., Panajotova V; Apigenex sro, Prague, Czech Republic., Roux J; Biomeostasis, La Penne sur Huveaune, France., Clemmensen C; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sylow L; Department of Biomedical Sciences, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark., Schneeberger M; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut, USA.; Wu Tsai Institute for Mind and Brain, Yale University, New Haven, Connecticut, USA., Beck-Sickinger AG; Faculty of Life Sciences, Leipzig University, Leipzig, Germany., Pedersen SL; Pephexia Therapeutics ApS, Frederiksberg, Denmark., Fosgerau K; Pephexia Therapeutics ApS, Frederiksberg, Denmark.
Source: Journal of cachexia, sarcopenia and muscle [J Cachexia Sarcopenia Muscle] 2026 Jun; Vol. 17 (3), pp. e70318.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders Country of Publication: Germany NLM ID: 101552883 Publication Model: Print Cited Medium: Internet ISSN: 2190-6009 (Electronic) Linking ISSN: 21905991 NLM ISO Abbreviation: J Cachexia Sarcopenia Muscle Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2190-6009
DOI:10.1002/jcsm.70318