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Novel Long-Acting Ghrelin Analogue PEP-064 Restores Energy Balance in C26 and Lewis Lung Carcinoma-Induced cachexia in Mice.

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Title: Novel Long-Acting Ghrelin Analogue PEP-064 Restores Energy Balance in C26 and Lewis Lung Carcinoma-Induced cachexia in Mice.
Authors: Hunt JE; Pephexia Therapeutics ApS, Frederiksberg, Denmark., Lund C; Pephexia Therapeutics ApS, Frederiksberg, Denmark., Chen B; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut, USA., Diaz AR; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut, USA., Dmytriyeva O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Marcotorchino J; Biomeostasis, La Penne sur Huveaune, France., Löbner K; Faculty of Life Sciences, Leipzig University, Leipzig, Germany., Mörl K; Faculty of Life Sciences, Leipzig University, Leipzig, Germany., Andersen NR; Department of Biomedical Sciences, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark., Ogueboule ZKJ; Department of Biomedical Sciences, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark., Frank E; Department of Biomedical Sciences, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark., Stöhr J; Apigenex sro, Prague, Czech Republic., Meseguer D; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut, USA., Panajotova V; Apigenex sro, Prague, Czech Republic., Roux J; Biomeostasis, La Penne sur Huveaune, France., Clemmensen C; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sylow L; Department of Biomedical Sciences, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark., Schneeberger M; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut, USA.; Wu Tsai Institute for Mind and Brain, Yale University, New Haven, Connecticut, USA., Beck-Sickinger AG; Faculty of Life Sciences, Leipzig University, Leipzig, Germany., Pedersen SL; Pephexia Therapeutics ApS, Frederiksberg, Denmark., Fosgerau K; Pephexia Therapeutics ApS, Frederiksberg, Denmark.
Source: Journal of cachexia, sarcopenia and muscle [J Cachexia Sarcopenia Muscle] 2026 Jun; Vol. 17 (3), pp. e70318.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders Country of Publication: Germany NLM ID: 101552883 Publication Model: Print Cited Medium: Internet ISSN: 2190-6009 (Electronic) Linking ISSN: 21905991 NLM ISO Abbreviation: J Cachexia Sarcopenia Muscle Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Novel Long-Acting Ghrelin Analogue PEP-064 Restores Energy Balance in C26 and Lewis Lung Carcinoma-Induced cachexia in Mice.
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  Data: <searchLink fieldCode="AU" term="%22Hunt+JE%22">Hunt JE</searchLink>; Pephexia Therapeutics ApS, Frederiksberg, Denmark.<br /><searchLink fieldCode="AU" term="%22Lund+C%22">Lund C</searchLink>; Pephexia Therapeutics ApS, Frederiksberg, Denmark.<br /><searchLink fieldCode="AU" term="%22Chen+B%22">Chen B</searchLink>; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Diaz+AR%22">Diaz AR</searchLink>; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Dmytriyeva+O%22">Dmytriyeva O</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Marcotorchino+J%22">Marcotorchino J</searchLink>; Biomeostasis, La Penne sur Huveaune, France.<br /><searchLink fieldCode="AU" term="%22Löbner+K%22">Löbner K</searchLink>; Faculty of Life Sciences, Leipzig University, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Mörl+K%22">Mörl K</searchLink>; Faculty of Life Sciences, Leipzig University, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Andersen+NR%22">Andersen NR</searchLink>; Department of Biomedical Sciences, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Ogueboule+ZKJ%22">Ogueboule ZKJ</searchLink>; Department of Biomedical Sciences, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Frank+E%22">Frank E</searchLink>; Department of Biomedical Sciences, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Stöhr+J%22">Stöhr J</searchLink>; Apigenex sro, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Meseguer+D%22">Meseguer D</searchLink>; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Panajotova+V%22">Panajotova V</searchLink>; Apigenex sro, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Roux+J%22">Roux J</searchLink>; Biomeostasis, La Penne sur Huveaune, France.<br /><searchLink fieldCode="AU" term="%22Clemmensen+C%22">Clemmensen C</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Sylow+L%22">Sylow L</searchLink>; Department of Biomedical Sciences, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Schneeberger+M%22">Schneeberger M</searchLink>; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut, USA.; Wu Tsai Institute for Mind and Brain, Yale University, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Beck-Sickinger+AG%22">Beck-Sickinger AG</searchLink>; Faculty of Life Sciences, Leipzig University, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Pedersen+SL%22">Pedersen SL</searchLink>; Pephexia Therapeutics ApS, Frederiksberg, Denmark.<br /><searchLink fieldCode="AU" term="%22Fosgerau+K%22">Fosgerau K</searchLink>; Pephexia Therapeutics ApS, Frederiksberg, Denmark.
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  Data: <searchLink fieldCode="JN" term="%22101552883%22">Journal of cachexia, sarcopenia and muscle</searchLink> [J Cachexia Sarcopenia Muscle] 2026 Jun; Vol. 17 (3), pp. e70318.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons+Ltd+on+behalf+of+Society+on+Sarcopenia%2C+Cachexia+and+Wasting+Disorders%22">John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101552883 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2190-6009 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221905991%22">21905991 </searchLink><i>NLM ISO Abbreviation: </i>J Cachexia Sarcopenia Muscle <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun
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