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Exosomal integrin αvβ3 derived from colorectal cancer promotes the liver pre-metastatic niche formation by inducing cancer-associated fibroblasts activation.

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Title: Exosomal integrin αvβ3 derived from colorectal cancer promotes the liver pre-metastatic niche formation by inducing cancer-associated fibroblasts activation.
Authors: Yu J; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China., Xiang J; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China., Yao L; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China., Wang S; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China., Liu Y; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China., Chen E; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China., Liu X; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China., Wu J; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China., Wang Y; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China., Zhao L; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China. zhaoleilei0507@126.com.
Source: Clinical and experimental medicine [Clin Exp Med] 2026 May 31; Vol. 26 (1). Date of Electronic Publication: 2026 May 31.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 100973405 Publication Model: Electronic Cited Medium: Internet ISSN: 1591-9528 (Electronic) Linking ISSN: 15918890 NLM ISO Abbreviation: Clin Exp Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Exosomal integrin αvβ3 derived from colorectal cancer promotes the liver pre-metastatic niche formation by inducing cancer-associated fibroblasts activation.
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  Data: <searchLink fieldCode="AU" term="%22Yu+J%22">Yu J</searchLink>; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China.<br /><searchLink fieldCode="AU" term="%22Xiang+J%22">Xiang J</searchLink>; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China.<br /><searchLink fieldCode="AU" term="%22Yao+L%22">Yao L</searchLink>; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China.<br /><searchLink fieldCode="AU" term="%22Chen+E%22">Chen E</searchLink>; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China.<br /><searchLink fieldCode="AU" term="%22Wu+J%22">Wu J</searchLink>; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China.<br /><searchLink fieldCode="AU" term="%22Zhao+L%22">Zhao L</searchLink>; Cancer Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong an Road, Beijing, Xi Cheng District, 100053, China. zhaoleilei0507@126.com.
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  Data: <searchLink fieldCode="JN" term="%22100973405%22">Clinical and experimental medicine</searchLink> [Clin Exp Med] 2026 May 31; Vol. 26 (1). <i>Date of Electronic Publication: </i>2026 May 31.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag+Italia%22">Springer-Verlag Italia </searchLink><i>Country of Publication: </i>Italy <i>NLM ID: </i>100973405 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1591-9528 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215918890%22">15918890 </searchLink><i>NLM ISO Abbreviation: </i>Clin Exp Med <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s10238-026-02193-5
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        Text: English
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      – TitleFull: Exosomal integrin αvβ3 derived from colorectal cancer promotes the liver pre-metastatic niche formation by inducing cancer-associated fibroblasts activation.
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              Text: 2026 May 31
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