View in EDS HTML Full Text PDF Full Text

Innovation in sepsis trials: rethinking endpoints, statistics and patient stratification.

Saved in:
Bibliographic Details
Title: Innovation in sepsis trials: rethinking endpoints, statistics and patient stratification.
Authors: David S; Institute of Intensive Care Medicine, University Hospital Zurich & University of Zurich, Rämistrasse 100, 8032, Zurich, Switzerland. Sascha.david@usz.ch.; Department of Nephrology, Medical School Hannover, Hannover, Germany. Sascha.david@usz.ch.; German Sepsis Society (DSG), Berlin, Germany. Sascha.david@usz.ch., Leone M; Department of Anesthesiology and Intensive Care Medicine, Nord Hospital, Assistance Publique Hôpitaux Universitaires de Marseille, Aix Marseille University, Marseille, France., Girardis M; Department of Anesthesia and ICU, University Hospital of Modena, Modena, Italy., Müller MM; Institute of Intensive Care Medicine, University Hospital Zurich & University of Zurich, Rämistrasse 100, 8032, Zurich, Switzerland., Gavrilovic S; Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.; Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, Serbia., Domizi R; Clinic of Anesthesia and Intensive Care, Department of Biomedical Sciences and Public Health, Università Politecnica Delle Marche, Ancona, Italy.; Clinic of Anesthesia and Intensive Care, Azienda Ospedaliero Universitaria Delle Marche, Torrette, Italy., Damiani E; Clinic of Anesthesia and Intensive Care, Department of Biomedical Sciences and Public Health, Università Politecnica Delle Marche, Ancona, Italy.; Clinic of Anesthesia and Intensive Care, Azienda Ospedaliero Universitaria Delle Marche, Torrette, Italy., Martin-Loeches I; Department of Intensive Care Medicine, Multidisciplinary Intensive Care Research Organization (MICRO), St James's Hospital, Dublin, D08 NHY1, Ireland.; School of Medicine, Trinity College Dublin, Dublin, D02 PN40, Ireland.; Trinity Centre for Biomedical Engineering, Dublin, Ireland., Ferrer R; Intensive Care Department, Vall d'Hebron Hospital Universitari, SODIR Research Group, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain.; Department of Medicine, Universitat Autònoma de Barcelona, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain., Bode C; Department of Anesthesiology and Intensive Care Medicine, University of Bonn, University Hospital Bonn, Bonn, Germany., Chousterman B; Université Paris Cité, INSERM U942 MASCOT, 75006, Paris, France.; Department of Anesthesia and Critical Care, AP-HP, Hôpital Lariboisière, 75010, Paris, France., Russell L; Department of Intensive Care, Herlev-Gentofte Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark.
Source: Intensive care medicine experimental [Intensive Care Med Exp] 2026 Jun 01; Vol. 14 (1). Date of Electronic Publication: 2026 Jun 01.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer-Verlag, GmbH Country of Publication: Germany NLM ID: 101645149 Publication Model: Electronic Cited Medium: Print ISSN: 2197-425X (Print) Linking ISSN: 2197425X NLM ISO Abbreviation: Intensive Care Med Exp Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42223758
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Innovation in sepsis trials: rethinking endpoints, statistics and patient stratification.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22David+S%22">David S</searchLink>; Institute of Intensive Care Medicine, University Hospital Zurich & University of Zurich, Rämistrasse 100, 8032, Zurich, Switzerland. Sascha.david@usz.ch.; Department of Nephrology, Medical School Hannover, Hannover, Germany. Sascha.david@usz.ch.; German Sepsis Society (DSG), Berlin, Germany. Sascha.david@usz.ch.<br /><searchLink fieldCode="AU" term="%22Leone+M%22">Leone M</searchLink>; Department of Anesthesiology and Intensive Care Medicine, Nord Hospital, Assistance Publique Hôpitaux Universitaires de Marseille, Aix Marseille University, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Girardis+M%22">Girardis M</searchLink>; Department of Anesthesia and ICU, University Hospital of Modena, Modena, Italy.<br /><searchLink fieldCode="AU" term="%22Müller+MM%22">Müller MM</searchLink>; Institute of Intensive Care Medicine, University Hospital Zurich & University of Zurich, Rämistrasse 100, 8032, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gavrilovic+S%22">Gavrilovic S</searchLink>; Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.; Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, Serbia.<br /><searchLink fieldCode="AU" term="%22Domizi+R%22">Domizi R</searchLink>; Clinic of Anesthesia and Intensive Care, Department of Biomedical Sciences and Public Health, Università Politecnica Delle Marche, Ancona, Italy.; Clinic of Anesthesia and Intensive Care, Azienda Ospedaliero Universitaria Delle Marche, Torrette, Italy.<br /><searchLink fieldCode="AU" term="%22Damiani+E%22">Damiani E</searchLink>; Clinic of Anesthesia and Intensive Care, Department of Biomedical Sciences and Public Health, Università Politecnica Delle Marche, Ancona, Italy.; Clinic of Anesthesia and Intensive Care, Azienda Ospedaliero Universitaria Delle Marche, Torrette, Italy.<br /><searchLink fieldCode="AU" term="%22Martin-Loeches+I%22">Martin-Loeches I</searchLink>; Department of Intensive Care Medicine, Multidisciplinary Intensive Care Research Organization (MICRO), St James's Hospital, Dublin, D08 NHY1, Ireland.; School of Medicine, Trinity College Dublin, Dublin, D02 PN40, Ireland.; Trinity Centre for Biomedical Engineering, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Ferrer+R%22">Ferrer R</searchLink>; Intensive Care Department, Vall d'Hebron Hospital Universitari, SODIR Research Group, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain.; Department of Medicine, Universitat Autònoma de Barcelona, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Bode+C%22">Bode C</searchLink>; Department of Anesthesiology and Intensive Care Medicine, University of Bonn, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Chousterman+B%22">Chousterman B</searchLink>; Université Paris Cité, INSERM U942 MASCOT, 75006, Paris, France.; Department of Anesthesia and Critical Care, AP-HP, Hôpital Lariboisière, 75010, Paris, France.<br /><searchLink fieldCode="AU" term="%22Russell+L%22">Russell L</searchLink>; Department of Intensive Care, Herlev-Gentofte Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101645149%22">Intensive care medicine experimental</searchLink> [Intensive Care Med Exp] 2026 Jun 01; Vol. 14 (1). <i>Date of Electronic Publication: </i>2026 Jun 01.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Review
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%2C+GmbH%22">Springer-Verlag, GmbH </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101645149 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2197-425X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222197425X%22">2197425X </searchLink><i>NLM ISO Abbreviation: </i>Intensive Care Med Exp <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42223758
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1186/s40635-026-00911-7
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Innovation in sepsis trials: rethinking endpoints, statistics and patient stratification.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: David S
      – PersonEntity:
          Name:
            NameFull: Leone M
      – PersonEntity:
          Name:
            NameFull: Girardis M
      – PersonEntity:
          Name:
            NameFull: Müller MM
      – PersonEntity:
          Name:
            NameFull: Gavrilovic S
      – PersonEntity:
          Name:
            NameFull: Domizi R
      – PersonEntity:
          Name:
            NameFull: Damiani E
      – PersonEntity:
          Name:
            NameFull: Martin-Loeches I
      – PersonEntity:
          Name:
            NameFull: Ferrer R
      – PersonEntity:
          Name:
            NameFull: Bode C
      – PersonEntity:
          Name:
            NameFull: Chousterman B
      – PersonEntity:
          Name:
            NameFull: Russell L
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 06
              Text: 2026 Jun 01
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-print
              Value: 2197-425X
          Numbering:
            – Type: volume
              Value: 14
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Intensive care medicine experimental
              Type: main
ResultId 1