Targeting tumor-specific T cells with LAG3-directed interleukin-2 prevents T-cell exhaustion and reinvigorates antitumor immunity.
Saved in:
| Title: | Targeting tumor-specific T cells with LAG3-directed interleukin-2 prevents T-cell exhaustion and reinvigorates antitumor immunity. |
|---|---|
| Authors: | Yu X; Changping Laboratory, Beijing, China., Liao H; Changping Laboratory, Beijing, China., Lv J; Changping Laboratory, Beijing, China., Sun Y; Changping Laboratory, Beijing, China., Zhang R; Changping Laboratory, Beijing, China., Chen Y; Changping Laboratory, Beijing, China., Lin Y; Changping Laboratory, Beijing, China., Liu L; Changping Laboratory, Beijing, China., Li S; Changping Laboratory, Beijing, China.; Center for Cancer Biology, School of Basic Medical Sciences, Tsinghua University, Beijing, China.; State Key Laboratory of Molecular Oncology, Tsinghua University, Beijing, China., Tang H; Department of Medical Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Jia P; Changping Laboratory, Beijing, China.; Department of Lymphoma, Department of Breast Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China., Shao B; Department of Lymphoma, Department of Breast Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China., Yang Z; Changping Laboratory, Beijing, China., Fu YX; Changping Laboratory, Beijing, China. yangxinfu@mail.tsinghua.edu.cn.; Center for Cancer Biology, School of Basic Medical Sciences, Tsinghua University, Beijing, China. yangxinfu@mail.tsinghua.edu.cn.; State Key Laboratory of Molecular Oncology, Tsinghua University, Beijing, China. yangxinfu@mail.tsinghua.edu.cn., Ren Z; Changping Laboratory, Beijing, China. renzhenhua@cpl.ac.cn.; Department of Lymphoma, Department of Breast Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China. renzhenhua@cpl.ac.cn. |
| Source: | Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Jun 02; Vol. 11 (1). Date of Electronic Publication: 2026 Jun 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 2059-3635 |
|---|---|
| DOI: | 10.1038/s41392-026-02667-8 |
