Structural basis for uracil removal from DNA by human SMUG1.

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Title: Structural basis for uracil removal from DNA by human SMUG1.
Authors: Ludäscher JM; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden., Scaletti Hutchinson E; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden., Vila-Julià G; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Jemth AS; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden., Shahid S; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden., Wiita E; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden., Cabeza de Vaca I; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Pach S; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Gajdos L; Large Scale Structures group, Institut Laue-Langevin (ILL), Grenoble, France., Aggarwal S; European Spallation Source (ESS), Lund, Sweden.; Division of Computational Chemistry, Lund University, Lund, Sweden., Walse E; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden., Mortusewicz O; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden., Helleday T; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden., Carlsson J; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Stenmark P; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden. stenmark@dbb.su.se.
Source: Nature communications [Nat Commun] 2026 Jun 02; Vol. 17 (1). Date of Electronic Publication: 2026 Jun 02.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-026-72937-0