Structural basis for uracil removal from DNA by human SMUG1.

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Title: Structural basis for uracil removal from DNA by human SMUG1.
Authors: Ludäscher JM; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden., Scaletti Hutchinson E; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden., Vila-Julià G; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Jemth AS; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden., Shahid S; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden., Wiita E; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden., Cabeza de Vaca I; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Pach S; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Gajdos L; Large Scale Structures group, Institut Laue-Langevin (ILL), Grenoble, France., Aggarwal S; European Spallation Source (ESS), Lund, Sweden.; Division of Computational Chemistry, Lund University, Lund, Sweden., Walse E; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden., Mortusewicz O; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden., Helleday T; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden., Carlsson J; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Stenmark P; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden. stenmark@dbb.su.se.
Source: Nature communications [Nat Commun] 2026 Jun 02; Vol. 17 (1). Date of Electronic Publication: 2026 Jun 02.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Structural basis for uracil removal from DNA by human SMUG1.
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  Data: <searchLink fieldCode="AU" term="%22Ludäscher+JM%22">Ludäscher JM</searchLink>; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Scaletti+Hutchinson+E%22">Scaletti Hutchinson E</searchLink>; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Vila-Julià+G%22">Vila-Julià G</searchLink>; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Jemth+AS%22">Jemth AS</searchLink>; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Shahid+S%22">Shahid S</searchLink>; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Wiita+E%22">Wiita E</searchLink>; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Cabeza+de+Vaca+I%22">Cabeza de Vaca I</searchLink>; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Pach+S%22">Pach S</searchLink>; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Gajdos+L%22">Gajdos L</searchLink>; Large Scale Structures group, Institut Laue-Langevin (ILL), Grenoble, France.<br /><searchLink fieldCode="AU" term="%22Aggarwal+S%22">Aggarwal S</searchLink>; European Spallation Source (ESS), Lund, Sweden.; Division of Computational Chemistry, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Walse+E%22">Walse E</searchLink>; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Mortusewicz+O%22">Mortusewicz O</searchLink>; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Helleday+T%22">Helleday T</searchLink>; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Carlsson+J%22">Carlsson J</searchLink>; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Stenmark+P%22">Stenmark P</searchLink>; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden. stenmark@dbb.su.se.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Jun 02; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Jun 02.
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