Phosphoproteomic profiling reveals post-translational dysregulation in Huntington's disease patient-derived neurons.

Saved in:
Bibliographic Details
Title: Phosphoproteomic profiling reveals post-translational dysregulation in Huntington's disease patient-derived neurons.
Authors: Danics L; Institute of Clinical Pathophysiology, Semmelweis University, Budapest, Hungary.; Hungarian Centre of Excellence for Molecular Medicine-Semmelweis University (HCEMM-SU), Neurobiology and Neurodegenerative Diseases Research Group, Budapest, Hungary.; HUN-REN-SU Cerebrovascular and Neurocognitive Diseases Research Group, Budapest, Hungary., Muralidharan C; Hungarian Centre of Excellence for Molecular Medicine-Semmelweis University (HCEMM-SU), Neurobiology and Neurodegenerative Diseases Research Group, Budapest, Hungary.; Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, Lund, Sweden., Varga Á; Institute of Clinical Pathophysiology, Semmelweis University, Budapest, Hungary.; Hungarian Centre of Excellence for Molecular Medicine-Semmelweis University (HCEMM-SU), Neurobiology and Neurodegenerative Diseases Research Group, Budapest, Hungary.; HUN-REN-SZTAKI-SU Rejuvenation Research Group, HUN-REN Office for Supported Research Groups (TKI), Budapest, Hungary., Rezeli M; Division for Biomedical Engineering, Department of Biomedical Engineering, Lund University, Lund, Sweden.; BioMS-Swedish National Infrastructure for Biological Mass Spectrometry, Lund University, Lund, Sweden., Gil J; Clinical Chemistry, Department of Translational Medicine, Lund University, Lund, Sweden., Abbas AA; Institute of Clinical Pathophysiology, Semmelweis University, Budapest, Hungary.; Hungarian Centre of Excellence for Molecular Medicine-Semmelweis University (HCEMM-SU), Neurobiology and Neurodegenerative Diseases Research Group, Budapest, Hungary., Pap Á; Single Cell Omics Advanced Core Facility, Hungarian Centre of Excellence for Molecular Medicine, Szeged, Hungary.; Laboratory of Proteomics, Complex Molecular and Cell Biology Service Centre, HUN-REN Biological Research Centre, Szeged, Hungary., Park AS; Faculty of Pharmacy, University of Montreal, Montreal, QC, Canada.; Centre de Recherche Sur Le Cerveau Et L'apprentissage (CIRCA), University of Montreal, Montreal, QC, Canada., Cserhalmi M; MTA-HUN-REN RCNS Lendület 'Momentum' DNA Repair Research Group, Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary., Legault EM; Faculty of Pharmacy, University of Montreal, Montreal, QC, Canada.; Centre de Recherche Sur Le Cerveau Et L'apprentissage (CIRCA), University of Montreal, Montreal, QC, Canada., Sőth Á; Institute of Clinical Pathophysiology, Semmelweis University, Budapest, Hungary.; Hungarian Centre of Excellence for Molecular Medicine-Semmelweis University (HCEMM-SU), Neurobiology and Neurodegenerative Diseases Research Group, Budapest, Hungary., Jamniczky D; Institute of Clinical Pathophysiology, Semmelweis University, Budapest, Hungary.; Hungarian Centre of Excellence for Molecular Medicine-Semmelweis University (HCEMM-SU), Neurobiology and Neurodegenerative Diseases Research Group, Budapest, Hungary., Zsoldos R; Institute of Clinical Pathophysiology, Semmelweis University, Budapest, Hungary.; Hungarian Centre of Excellence for Molecular Medicine-Semmelweis University (HCEMM-SU), Neurobiology and Neurodegenerative Diseases Research Group, Budapest, Hungary.; HUN-REN-SZTAKI-SU Rejuvenation Research Group, HUN-REN Office for Supported Research Groups (TKI), Budapest, Hungary., Barker RA; Cambridge Stem Cell Institute and John Van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Forvie Site, Cambridge, UK., Róna G; MTA-HUN-REN RCNS Lendület 'Momentum' DNA Repair Research Group, Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA., Drouin-Ouellet J; Faculty of Pharmacy, University of Montreal, Montreal, QC, Canada.; Centre de Recherche Sur Le Cerveau Et L'apprentissage (CIRCA), University of Montreal, Montreal, QC, Canada., Markó-Varga G; BioMS-Swedish National Infrastructure for Biological Mass Spectrometry, Lund University, Lund, Sweden., Darula Z; Single Cell Omics Advanced Core Facility, Hungarian Centre of Excellence for Molecular Medicine, Szeged, Hungary.; Laboratory of Proteomics, Complex Molecular and Cell Biology Service Centre, HUN-REN Biological Research Centre, Szeged, Hungary., Pircs K; Institute of Clinical Pathophysiology, Semmelweis University, Budapest, Hungary. pircs.karolina@semmelweis.hu.; Hungarian Centre of Excellence for Molecular Medicine-Semmelweis University (HCEMM-SU), Neurobiology and Neurodegenerative Diseases Research Group, Budapest, Hungary. pircs.karolina@semmelweis.hu.; Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, Lund, Sweden. pircs.karolina@semmelweis.hu.; HUN-REN-SZTAKI-SU Rejuvenation Research Group, HUN-REN Office for Supported Research Groups (TKI), Budapest, Hungary. pircs.karolina@semmelweis.hu.
Source: Cellular & molecular biology letters [Cell Mol Biol Lett] 2026 Jun 02; Vol. 31 (1). Date of Electronic Publication: 2026 Jun 02.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9607427 Publication Model: Electronic Cited Medium: Internet ISSN: 1689-1392 (Electronic) Linking ISSN: 14258153 NLM ISO Abbreviation: Cell Mol Biol Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1689-1392
DOI:10.1186/s11658-026-00948-2