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Identification of immunosuppressive neutrophils using multi-omics: why functional testing remains key.

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Title: Identification of immunosuppressive neutrophils using multi-omics: why functional testing remains key.
Authors: van Oosterom F; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.; Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands., Gankema AAF; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.; Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands., Rojas-Rodriguez F; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.; Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands., Hoogendijk AJ; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands., Kuijpers TW; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.; Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.
Source: Frontiers in immunology [Front Immunol] 2026 May 18; Vol. 17, pp. 1814355. Date of Electronic Publication: 2026 May 18 (Print Publication: 2026).
Publication Type: Journal Article; Review
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22van+Oosterom+F%22">van Oosterom F</searchLink>; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.; Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Gankema+AAF%22">Gankema AAF</searchLink>; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.; Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Rojas-Rodriguez+F%22">Rojas-Rodriguez F</searchLink>; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.; Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Hoogendijk+AJ%22">Hoogendijk AJ</searchLink>; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kuijpers+TW%22">Kuijpers TW</searchLink>; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.; Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 May 18; Vol. 17, pp. 1814355. <i>Date of Electronic Publication: </i>2026 May 18 (<i>Print Publication: </i>2026).
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