Progranulin deficiency induces premature vascular senescence and dysfunction.
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| Title: | Progranulin deficiency induces premature vascular senescence and dysfunction. |
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| Authors: | Luvizotto RAM; Department of Physiology and Cell Biology, University of South Alabama, Mobile, Alabama, United States.; Institute of Health Sciences, Federal University of Mato Grosso, Sinop, Brazil., Nascimento AF; Department of Physiology and Cell Biology, University of South Alabama, Mobile, Alabama, United States.; Institute of Health Sciences, Federal University of Mato Grosso, Sinop, Brazil., Pimenta GF; Department of Physiology and Cell Biology, University of South Alabama, Mobile, Alabama, United States.; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil., de Costa RM; Department of Physiology and Cell Biology, University of South Alabama, Mobile, Alabama, United States.; Institute of Health Sciences, Federal University of Jatai, Jatai, Brazil., Beling T; Department of Physiology and Cell Biology, University of South Alabama, Mobile, Alabama, United States., Singh S; Children's Hospital of Philadelphia (CHOP), Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States., Alves JV; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil., Awata WMC; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil., Russ A; Department of Pharmacology, University of South Alabama, Mobile, Alabama, United States., Haastrup AI; Department of Pharmacology, University of South Alabama, Mobile, Alabama, United States., Cuevas RA; Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States., Behzadi P; Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States., St Hilaire C; Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.; Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.; Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States., Roberts JT; Department of Pharmacology, University of South Alabama, Mobile, Alabama, United States., Bruder A; Department of Physiology and Cell Biology, University of South Alabama, Mobile, Alabama, United States., Bruder-Nascimento T; Department of Physiology and Cell Biology, University of South Alabama, Mobile, Alabama, United States.; Center for Lung Biology, University of South Alabama, Mobile, Alabama, United States. |
| Source: | American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2026 Jul 01; Vol. 331 (1), pp. H260-H275. Date of Electronic Publication: 2026 Jun 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901228 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1539 (Electronic) Linking ISSN: 03636135 NLM ISO Abbreviation: Am J Physiol Heart Circ Physiol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1522-1539 |
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| DOI: | 10.1152/ajpheart.00012.2026 |
