Neutrophil-derived itaconate facilitates tiered pulmonary inflammation via Kdm5b-associated epigenetic remodeling in alveolar macrophages.

Saved in:
Bibliographic Details
Title: Neutrophil-derived itaconate facilitates tiered pulmonary inflammation via Kdm5b-associated epigenetic remodeling in alveolar macrophages.
Authors: Lim G; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Korea., Kim J; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea; Department of Bioinformatics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Korea., Park D; Department of Biochemistry, College of Natural Sciences, Chungnam National University, Daejeon, Korea., Lee JH; Department of Biological Sciences, Sungkyunkwan University, Suwon, Korea., Roh YJ; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Korea., Yang M; Department of Biological Sciences, Sungkyunkwan University, Suwon, Korea., Lee S; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Korea., Yang S; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Korea., Baek S; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Korea., Park J; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Korea., Lim HC; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Korea; Environmental Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea., Lee JH; Environmental Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea., Kim S; Environmental Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea., Seo H; Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea., Kim YH; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Korea; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea., Jung SM; Department of Biological Sciences, Sungkyunkwan University, Suwon, Korea., Yang H; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea., Sun P; Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea., Lee SE; Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea., Kang YE; Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea., Park YJ; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Korea; Environmental Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea., Son YM; Department of Systems Biotechnology, Chung-Ang University, Anseong 17456, Republic of Korea., Yi HS; Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea., Hong JY; Department of Systems Biology, Yonsei University, Seoul, Korea., Moita LF; Center for Disease Mechanisms Research, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal., Kang DH; Institute for Medical Sciences, College of Medicine, Chungnam National University, Daejeon, Korea. Electronic address: ibelieveu113@cnuh.co.kr., Kim H; Department of Biological Sciences, Sungkyunkwan University, Suwon, Korea. Electronic address: hongkim@skku.edu., Kim C; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea; Department of Bioinformatics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Korea. Electronic address: kimchuna@kribb.re.kr., Yoon SJ; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Korea; Environmental Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea. Electronic address: sjy04@kribb.re.kr., Choi DW; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Korea; National Research Laboratory for Convergence Degradation Biology, Korea University, Seoul, Korea. Electronic address: dongwook_choi@korea.ac.kr.
Source: Cell reports [Cell Rep] 2026 Jun 23; Vol. 45 (6), pp. 117412. Date of Electronic Publication: 2026 Jun 02.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2211-1247
DOI:10.1016/j.celrep.2026.117412