Spatially resolved single-cell landscape of tumor immunotypes reveals the central role of interferon signaling and plasmacytoid dendritic cells in triple-negative breast cancer.

Saved in:
Bibliographic Details
Title: Spatially resolved single-cell landscape of tumor immunotypes reveals the central role of interferon signaling and plasmacytoid dendritic cells in triple-negative breast cancer.
Authors: Liu Y; Department of Quantitative Health Sciences, Mayo Clinic in Florida, Jacksonville, Florida, USA chumsri.saranya@mayo.edu Liu.Yi1@mayo.edu.; Department of Pioneering Science, Office of Core Shared Services, Mayo Clinic in Florida, Jacksonville, Florida, USA., Carter JM; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada., Ma Y; Department of Quantitative Health Sciences, Mayo Clinic in Florida, Jacksonville, Florida, USA., Deshmukh SK; Caris Life Sciences Inc Phoenix, Phoenix, Arizona, USA., Sledge GW Jr; Caris Life Sciences Inc Phoenix, Phoenix, Arizona, USA., Balko JM; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Kachergus JM; Department of Pioneering Science, Office of Core Shared Services, Mayo Clinic in Florida, Jacksonville, Florida, USA., Shi J; Department of Pioneering Science, Office of Core Shared Services, Mayo Clinic in Florida, Jacksonville, Florida, USA., Gregory M; NanoString Technologies Inc, Seattle, Washington, USA., Gong J; NanoString Technologies Inc, Seattle, Washington, USA., Joensuu H; Department of Oncology, HUS Helsinki University Hospital, Helsinki, Finland.; University of Helsinki, Helsinki, Finland., Perez EA; Department of Cancer Biology, Mayo Clinic in Florida, Jacksonville, Florida, USA., Stover D; The Ohio State University Comprehensive Cancer Center Arthur G James Cancer Hospital and Richard J Solove Research Institute, Columbus, Ohio, USA., Carey L; UNC School of Medicine, Chapel Hill, North Carolina, USA., Sikov WM; Department of Medicine, Brown University Warren Alpert Medical School, Providence, Rhode Island, USA.; Women & Infants Hospital of Rhode Island, Providence, Rhode Island, USA., Leon-Ferre R; Department of Oncology, Mayo Clinic Rochester, Rochester, Minnesota, USA., Knutson KL; Department of Immunology, Mayo Clinic in Florida, Jacksonville, Florida, USA., Boughey JC; Department of Surgery, Mayo Clinic Rochester, Rochester, Minnesota, USA., Ingle JN; Department of Oncology, Mayo Clinic Rochester, Rochester, Minnesota, USA., Kalari KR; Department of Quantitative Health Sciences, Mayo Clinic Rochester, Rochester, Minnesota, USA., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester, Rochester, Minnesota, USA., Asmann YW; Department of Quantitative Health Sciences, Mayo Clinic in Florida, Jacksonville, Florida, USA., Goetz MP; Department of Oncology, Mayo Clinic Rochester, Rochester, Minnesota, USA., Thompson EA; Department of Pioneering Science, Office of Core Shared Services, Mayo Clinic in Florida, Jacksonville, Florida, USA.; Department of Cancer Biology, Mayo Clinic in Florida, Jacksonville, Florida, USA., Chumsri S; Department of Hematology and Oncology, Mayo Clinic in Florida, Jacksonville, Florida, USA chumsri.saranya@mayo.edu Liu.Yi1@mayo.edu.
Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2026 Jun 03; Vol. 14 (6). Date of Electronic Publication: 2026 Jun 03.
Publication Type: Journal Article
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2051-1426
DOI:10.1136/jitc-2025-014020