3D chromatin architecture-related genes orchestrate LUAD evolution and therapy resistance: insights from integrative machine learning and spatial single-cell mapping.
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| Title: | 3D chromatin architecture-related genes orchestrate LUAD evolution and therapy resistance: insights from integrative machine learning and spatial single-cell mapping. |
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| Authors: | Jing Y; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Xing Y; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Liu Y; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Zhang N; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Pan Y; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Zhang W; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Zhu C; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Zhong Z; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Zhang G; Department of Thoracic Surgery, The First Affiliated Hospital of Henan University, Kaifeng, 475000, Henan, China. kfzgy315@163.com.; Kaifeng Key Laboratory of Translational Medicine for Thoracic Diseases, Kaifeng, 475000, Henan, China. kfzgy315@163.com., Li JC; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China. zjulijicheng@163.com.; Institute of Cell Biology, Zhejiang University, Hangzhou, 310030, China. zjulijicheng@163.com., Dong X; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China. dongxiaotao@henu.edu.cn.; Department of Thoracic Surgery, The First Affiliated Hospital of Henan University, Kaifeng, 475000, Henan, China. dongxiaotao@henu.edu.cn.; Kaifeng Key Laboratory of Translational Medicine for Thoracic Diseases, Kaifeng, 475000, Henan, China. dongxiaotao@henu.edu.cn.; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China. dongxiaotao@henu.edu.cn. |
| Source: | Functional & integrative genomics [Funct Integr Genomics] 2026 Jun 04; Vol. 26 (1). Date of Electronic Publication: 2026 Jun 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: Germany NLM ID: 100939343 Publication Model: Electronic Cited Medium: Internet ISSN: 1438-7948 (Electronic) Linking ISSN: 1438793X NLM ISO Abbreviation: Funct Integr Genomics Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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