The effects of amiodarone or dexamethasone on diclofenac-induced hepatotoxicity: Implications of P450s and SIRT1/Nrf2/NF-κb signaling pathways.
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| Title: | The effects of amiodarone or dexamethasone on diclofenac-induced hepatotoxicity: Implications of P450s and SIRT1/Nrf2/NF-κb signaling pathways. |
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| Authors: | Khatab LA; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt. Electronic address: LamiaaAAkhatab@pharm.dmu.edu.eg., Abdel-Raheem IT; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt., Ghoneim AI; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt; Department of Clinical Pharmacy & Pharmacy Practice, Faculty of Pharmacy and Drug Manufacturing, Pharos University in Alexandria, Alexandria, Egypt. Electronic address: asser.ghoneim@pharm.dmu.edu.eg. |
| Source: | Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2026 Jun; Vol. 54 (6), pp. 100317. Date of Electronic Publication: 2026 May 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1521-009X |
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| DOI: | 10.1016/j.dmd.2026.100317 |
