Lactylation-driven metabolic reprogramming promotes osteosarcoma malignancy via HDGF-mediated proliferation and immune modulation.
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| Title: | Lactylation-driven metabolic reprogramming promotes osteosarcoma malignancy via HDGF-mediated proliferation and immune modulation. |
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| Authors: | Hu S; Department of Spine Surgery, Zhongda Hospital Southeast University, Nanjing, China., Wu L; Department of Orthopedic Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China., Wang J; Department of Oncology, The First Affiliated Hospital of Dali University, Dali, China., Dai F; Chongqing Key Laboratory for the Mechanism and Intervention of Cancer Metastasis, Chongqing University Cancer Hospital, Chongqing University, Chongqing, China.; Department of Hepatobiliary Pancreatic Tumor Center, Chongqing University Cancer Hospital, Chongqing, China. |
| Source: | Frontiers in immunology [Front Immunol] 2026 May 20; Vol. 17, pp. 1836254. Date of Electronic Publication: 2026 May 20 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2026.1836254 |
