SLC22A3/OCT3 drives serotonin-mediated stemness in pancreatic cancer.

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Title: SLC22A3/OCT3 drives serotonin-mediated stemness in pancreatic cancer.
Authors: Krishna Kumar N; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Varadharaj V; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Gayen N; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Kaur AB; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Arikath K; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Shah A; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Mathivanan P; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Nallasamy P; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Alsafwani ZW; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Seshadri B; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Raut P; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Rauth S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Persinger J; Department of Genetics Cell Biology & Anatomy, University of Nebraska Medical Center, Omaha, NE, USA., Brahma S; Fred and Pamela Buffett Cancer Center, Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center at Omaha, Omaha, NE, USA; Department of Genetics Cell Biology & Anatomy, University of Nebraska Medical Center, Omaha, NE, USA., Schott M; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA; Fred and Pamela Buffett Cancer Center, Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center at Omaha, Omaha, NE, USA., Oberley-Deegan RE; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA; Fred and Pamela Buffett Cancer Center, Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center at Omaha, Omaha, NE, USA., Talmon GA; Department of Pathology, Microbiology & Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Cox JL; Department of Pathology, Microbiology & Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Batra SK; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA; Fred and Pamela Buffett Cancer Center, Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center at Omaha, Omaha, NE, USA. Electronic address: sbatra@unmc.edu., Ponnusamy MP; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA; Fred and Pamela Buffett Cancer Center, Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center at Omaha, Omaha, NE, USA. Electronic address: mpalanim@unmc.edu.
Source: Cell reports [Cell Rep] 2026 Jun 23; Vol. 45 (6), pp. 117387. Date of Electronic Publication: 2026 Jun 06.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2211-1247
DOI:10.1016/j.celrep.2026.117387