Intraindividual cognitive variability predicts amyloid beta, tau PET, and dementia conversion in Down syndrome: a potential marker of cognitive resilience.
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| Title: | Intraindividual cognitive variability predicts amyloid beta, tau PET, and dementia conversion in Down syndrome: a potential marker of cognitive resilience. |
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| Authors: | Fonseca LM; The Krieger Klein Alzheimer's Research Center, Rutgers Health, New Brunswick, New Jersey, USA.; Programa Terceira Idade (PROTER, Old Age Research Group), Department and Institute of Psychiatry, University of São Paulo School of Medicine, São Paulo, São Paulo, Brazil., Lila E; Department of Biostatistics, University of Washington, Seattle, Washington, USA., Shojaie A; Department of Biostatistics, University of Washington, Seattle, Washington, USA., Chhatwal J; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Brigham and Women's Hospital, Boston, Massachusetts, USA., Forlenza O; Laboratory of Neuroscience (LIM-27), Department and Institute of Psychiatry, University of São Paulo School of Medicine, São Paulo, São Paulo, Brazil., Beeri MS; The Krieger Klein Alzheimer's Research Center, Rutgers Health, New Brunswick, New Jersey, USA., Krinsky-McHale S; New York State Institute for Basic Research in Developmental Disabilities, New York, New York, USA., Cohen AD; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Christian BT; Wisconsin Alzheimer's Disease Research Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA., Head E; Department of Pathology and Laboratory Medicine, University of California, Irvine, California, USA., Mapstone M; Department of Neurology, Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, California, USA., Handen B; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Ances BM; Department of Neurology, Washington University in St Louis, St Louis, Missouri, USA., Grabowski T; Departments of Radiology and Neurology, University of Washington, Seattle, Washington, USA., Chaytor NS; Department of Community and Behavioral Health, Elson S Floyd College of Medicine, Washington State University, Spokane, Washington, USA., Zaman S; Department of Psychiatry, University of Cambridge, Cambridge, Cambridgeshire, UK.; Cambridgeshire & Peterborough NHS Foundation Trust, Cambridge, Cambridgeshire, UK. |
| Corporate Authors: | Alzheimer's Biomarkers Consortium‐ Down Syndrome (ABC‐DS) Investigators |
| Source: | Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Jun; Vol. 22 (6), pp. e71537. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1552-5279 |
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| DOI: | 10.1002/alz.71537 |
