Occult hepatitis B virus infection status is not associated with impaired efficacy of anti-CD19 CAR-T-cell therapy for lymphoma and shows a distinct immune toxicity profile: Results from the CART-SIE study.

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Title: Occult hepatitis B virus infection status is not associated with impaired efficacy of anti-CD19 CAR-T-cell therapy for lymphoma and shows a distinct immune toxicity profile: Results from the CART-SIE study.
Authors: Polverelli N; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Chiappella A; Division of Hematology and Stem Cell Transplantation Fondazione IRCCS Istituto Nazionale dei Tumori Milano Italy., Carniti C; Division of Hematology and Stem Cell Transplantation Fondazione IRCCS Istituto Nazionale dei Tumori Milano Italy., Zinzani P; IRCCS Azienda Ospedaliero-Universitaria di Bologna Istituto di Ematologia 'Seràgnoli' Bologna Italy.; Dipartimento di Scienze Mediche e Chirurgiche Università di Bologna Bologna Italy., Musso M; Onco-Hematology Unit and BMT La Maddalena Hospital Palermo Italy., Tisi MC; Hematology Unit San Bortolo Hospital, AULSS 8 Berica Vicenza Italy., Ciceri F; IRCCS Ospedale San Raffaele Milano Milano Italy., Cutini I; SOD Ematologia Azienda Ospedaliera Universitaria Careggi Firenze Italy., Santoro A; Department of Oncology and Hematology, IRCCS Humanitas Research Hospital Transplantation Unit Milano Italy., Chiusolo P; Dipartimento di Scienze di Laboratorio ed Ematologiche-Fondazione Policlinico Universitario Agostino Gemelli-IRCCS Roma Italy.; Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche Università Cattolica del Sacro Cuore Roma Italy., Barbui AM; Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII Bergamo Italy., Farina M; Unit of Blood Disease and Bone Marrow Transplantation, and Unit of Hematology University of Brescia, ASST Spedali Civili di Brescia Brescia Italy., Donzelli L; Hematology Department of Translational and Precision Medicine University Sapienza Roma Roma Italy., Brunello L; Hematology Department A.O.U. SS Antonio & Biagio and C. Arrigo Alessandria Italy., Martino M; Stem Cell Transplantation and Cellular Therapies Unit (CTMO) Grande Ospedale Metropolitano 'Bianchi-Melacrino-Morelli' Reggio Calabria Italy., Krampera M; Hematology and Bone Marrow Transplant Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine (DIMI) University of Verona Verona Italy., Castellino A; Department of Hematology Santa Croce e Carle Hospital Cuneo Italy., Grillo G; Department of Hematology ASST Grande Ospedale Metropolitano Niguarda Milano Italy., Botto B; Division of Hematology and Allogeneic Stem Cell Transplant Unit A.O.U. Città della Salute e della Scienza Turin Italy., Olivieri J; Hematology and Stem Cell Transplantation Unit, Udine University Hospital Azienda Sanitaria Universitaria Friuli Centrale Udine Italy., Clerico M; Hematology, Department of Molecular Biotechnologies and Health Sciences University of Torino Torino Italy., Musto P; Department of Precision and Regenerative Medicine and Ionian Area 'Aldo Moro' University School of Medicine Bari Italy.; Unit of Hematology and Stem Cell Transplantation AOUC Policlinico Bari Italy., Olivieri A; Azienda Ospedali Riuniti di Ancona, Department of Hematology Ancona University Ancona Italy., Bianchessi A; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Defrancesco I; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Losi G; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Zerbi C; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Martini G; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Roncoroni E; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Gotti M; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Benevento MG; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Taurino A; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Fedina A; Data Office Fondazione Italiana Linfomi Alessandria Italy., Corradini P; Division of Hematology and Stem Cell Transplantation Fondazione IRCCS Istituto Nazionale dei Tumori Milano Italy.; Division of Hematology and Stem Cell Transplantation University of Milan Milano Italy., Arcaini L; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy.; Department of Molecular Medicine University of Pavia Pavia Italy.
Source: HemaSphere [Hemasphere] 2026 May 21; Vol. 10 (5), pp. e70362. Date of Electronic Publication: 2026 May 21 (Print Publication: 2026).
Publication Type: Letter
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2572-9241
DOI:10.1002/hem3.70362