Occult hepatitis B virus infection status is not associated with impaired efficacy of anti-CD19 CAR-T-cell therapy for lymphoma and shows a distinct immune toxicity profile: Results from the CART-SIE study.
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| Title: | Occult hepatitis B virus infection status is not associated with impaired efficacy of anti-CD19 CAR-T-cell therapy for lymphoma and shows a distinct immune toxicity profile: Results from the CART-SIE study. |
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| Authors: | Polverelli N; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Chiappella A; Division of Hematology and Stem Cell Transplantation Fondazione IRCCS Istituto Nazionale dei Tumori Milano Italy., Carniti C; Division of Hematology and Stem Cell Transplantation Fondazione IRCCS Istituto Nazionale dei Tumori Milano Italy., Zinzani P; IRCCS Azienda Ospedaliero-Universitaria di Bologna Istituto di Ematologia 'Seràgnoli' Bologna Italy.; Dipartimento di Scienze Mediche e Chirurgiche Università di Bologna Bologna Italy., Musso M; Onco-Hematology Unit and BMT La Maddalena Hospital Palermo Italy., Tisi MC; Hematology Unit San Bortolo Hospital, AULSS 8 Berica Vicenza Italy., Ciceri F; IRCCS Ospedale San Raffaele Milano Milano Italy., Cutini I; SOD Ematologia Azienda Ospedaliera Universitaria Careggi Firenze Italy., Santoro A; Department of Oncology and Hematology, IRCCS Humanitas Research Hospital Transplantation Unit Milano Italy., Chiusolo P; Dipartimento di Scienze di Laboratorio ed Ematologiche-Fondazione Policlinico Universitario Agostino Gemelli-IRCCS Roma Italy.; Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche Università Cattolica del Sacro Cuore Roma Italy., Barbui AM; Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII Bergamo Italy., Farina M; Unit of Blood Disease and Bone Marrow Transplantation, and Unit of Hematology University of Brescia, ASST Spedali Civili di Brescia Brescia Italy., Donzelli L; Hematology Department of Translational and Precision Medicine University Sapienza Roma Roma Italy., Brunello L; Hematology Department A.O.U. SS Antonio & Biagio and C. Arrigo Alessandria Italy., Martino M; Stem Cell Transplantation and Cellular Therapies Unit (CTMO) Grande Ospedale Metropolitano 'Bianchi-Melacrino-Morelli' Reggio Calabria Italy., Krampera M; Hematology and Bone Marrow Transplant Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine (DIMI) University of Verona Verona Italy., Castellino A; Department of Hematology Santa Croce e Carle Hospital Cuneo Italy., Grillo G; Department of Hematology ASST Grande Ospedale Metropolitano Niguarda Milano Italy., Botto B; Division of Hematology and Allogeneic Stem Cell Transplant Unit A.O.U. Città della Salute e della Scienza Turin Italy., Olivieri J; Hematology and Stem Cell Transplantation Unit, Udine University Hospital Azienda Sanitaria Universitaria Friuli Centrale Udine Italy., Clerico M; Hematology, Department of Molecular Biotechnologies and Health Sciences University of Torino Torino Italy., Musto P; Department of Precision and Regenerative Medicine and Ionian Area 'Aldo Moro' University School of Medicine Bari Italy.; Unit of Hematology and Stem Cell Transplantation AOUC Policlinico Bari Italy., Olivieri A; Azienda Ospedali Riuniti di Ancona, Department of Hematology Ancona University Ancona Italy., Bianchessi A; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Defrancesco I; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Losi G; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Zerbi C; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Martini G; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Roncoroni E; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Gotti M; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Benevento MG; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Taurino A; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy., Fedina A; Data Office Fondazione Italiana Linfomi Alessandria Italy., Corradini P; Division of Hematology and Stem Cell Transplantation Fondazione IRCCS Istituto Nazionale dei Tumori Milano Italy.; Division of Hematology and Stem Cell Transplantation University of Milan Milano Italy., Arcaini L; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy.; Department of Molecular Medicine University of Pavia Pavia Italy. |
| Source: | HemaSphere [Hemasphere] 2026 May 21; Vol. 10 (5), pp. e70362. Date of Electronic Publication: 2026 May 21 (Print Publication: 2026). |
| Publication Type: | Letter |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42256547 AccessLevel: 2 PubType: Editorial & Opinion PubTypeId: editorialOpinion PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Occult hepatitis B virus infection status is not associated with impaired efficacy of anti-CD19 CAR-T-cell therapy for lymphoma and shows a distinct immune toxicity profile: Results from the CART-SIE study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Polverelli+N%22">Polverelli N</searchLink>; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy.<br /><searchLink fieldCode="AU" term="%22Chiappella+A%22">Chiappella A</searchLink>; Division of Hematology and Stem Cell Transplantation Fondazione IRCCS Istituto Nazionale dei Tumori Milano Italy.<br /><searchLink fieldCode="AU" term="%22Carniti+C%22">Carniti C</searchLink>; Division of Hematology and Stem Cell Transplantation Fondazione IRCCS Istituto Nazionale dei Tumori Milano Italy.<br /><searchLink fieldCode="AU" term="%22Zinzani+P%22">Zinzani P</searchLink>; IRCCS Azienda Ospedaliero-Universitaria di Bologna Istituto di Ematologia 'Seràgnoli' Bologna Italy.; Dipartimento di Scienze Mediche e Chirurgiche Università di Bologna Bologna Italy.<br /><searchLink fieldCode="AU" term="%22Musso+M%22">Musso M</searchLink>; Onco-Hematology Unit and BMT La Maddalena Hospital Palermo Italy.<br /><searchLink fieldCode="AU" term="%22Tisi+MC%22">Tisi MC</searchLink>; Hematology Unit San Bortolo Hospital, AULSS 8 Berica Vicenza Italy.<br /><searchLink fieldCode="AU" term="%22Ciceri+F%22">Ciceri F</searchLink>; IRCCS Ospedale San Raffaele Milano Milano Italy.<br /><searchLink fieldCode="AU" term="%22Cutini+I%22">Cutini I</searchLink>; SOD Ematologia Azienda Ospedaliera Universitaria Careggi Firenze Italy.<br /><searchLink fieldCode="AU" term="%22Santoro+A%22">Santoro A</searchLink>; Department of Oncology and Hematology, IRCCS Humanitas Research Hospital Transplantation Unit Milano Italy.<br /><searchLink fieldCode="AU" term="%22Chiusolo+P%22">Chiusolo P</searchLink>; Dipartimento di Scienze di Laboratorio ed Ematologiche-Fondazione Policlinico Universitario Agostino Gemelli-IRCCS Roma Italy.; Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche Università Cattolica del Sacro Cuore Roma Italy.<br /><searchLink fieldCode="AU" term="%22Barbui+AM%22">Barbui AM</searchLink>; Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII Bergamo Italy.<br /><searchLink fieldCode="AU" term="%22Farina+M%22">Farina M</searchLink>; Unit of Blood Disease and Bone Marrow Transplantation, and Unit of Hematology University of Brescia, ASST Spedali Civili di Brescia Brescia Italy.<br /><searchLink fieldCode="AU" term="%22Donzelli+L%22">Donzelli L</searchLink>; Hematology Department of Translational and Precision Medicine University Sapienza Roma Roma Italy.<br /><searchLink fieldCode="AU" term="%22Brunello+L%22">Brunello L</searchLink>; Hematology Department A.O.U. SS Antonio & Biagio and C. Arrigo Alessandria Italy.<br /><searchLink fieldCode="AU" term="%22Martino+M%22">Martino M</searchLink>; Stem Cell Transplantation and Cellular Therapies Unit (CTMO) Grande Ospedale Metropolitano 'Bianchi-Melacrino-Morelli' Reggio Calabria Italy.<br /><searchLink fieldCode="AU" term="%22Krampera+M%22">Krampera M</searchLink>; Hematology and Bone Marrow Transplant Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine (DIMI) University of Verona Verona Italy.<br /><searchLink fieldCode="AU" term="%22Castellino+A%22">Castellino A</searchLink>; Department of Hematology Santa Croce e Carle Hospital Cuneo Italy.<br /><searchLink fieldCode="AU" term="%22Grillo+G%22">Grillo G</searchLink>; Department of Hematology ASST Grande Ospedale Metropolitano Niguarda Milano Italy.<br /><searchLink fieldCode="AU" term="%22Botto+B%22">Botto B</searchLink>; Division of Hematology and Allogeneic Stem Cell Transplant Unit A.O.U. Città della Salute e della Scienza Turin Italy.<br /><searchLink fieldCode="AU" term="%22Olivieri+J%22">Olivieri J</searchLink>; Hematology and Stem Cell Transplantation Unit, Udine University Hospital Azienda Sanitaria Universitaria Friuli Centrale Udine Italy.<br /><searchLink fieldCode="AU" term="%22Clerico+M%22">Clerico M</searchLink>; Hematology, Department of Molecular Biotechnologies and Health Sciences University of Torino Torino Italy.<br /><searchLink fieldCode="AU" term="%22Musto+P%22">Musto P</searchLink>; Department of Precision and Regenerative Medicine and Ionian Area 'Aldo Moro' University School of Medicine Bari Italy.; Unit of Hematology and Stem Cell Transplantation AOUC Policlinico Bari Italy.<br /><searchLink fieldCode="AU" term="%22Olivieri+A%22">Olivieri A</searchLink>; Azienda Ospedali Riuniti di Ancona, Department of Hematology Ancona University Ancona Italy.<br /><searchLink fieldCode="AU" term="%22Bianchessi+A%22">Bianchessi A</searchLink>; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy.<br /><searchLink fieldCode="AU" term="%22Defrancesco+I%22">Defrancesco I</searchLink>; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy.<br /><searchLink fieldCode="AU" term="%22Losi+G%22">Losi G</searchLink>; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy.<br /><searchLink fieldCode="AU" term="%22Zerbi+C%22">Zerbi C</searchLink>; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy.<br /><searchLink fieldCode="AU" term="%22Martini+G%22">Martini G</searchLink>; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy.<br /><searchLink fieldCode="AU" term="%22Roncoroni+E%22">Roncoroni E</searchLink>; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy.<br /><searchLink fieldCode="AU" term="%22Gotti+M%22">Gotti M</searchLink>; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy.<br /><searchLink fieldCode="AU" term="%22Benevento+MG%22">Benevento MG</searchLink>; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy.<br /><searchLink fieldCode="AU" term="%22Taurino+A%22">Taurino A</searchLink>; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy.<br /><searchLink fieldCode="AU" term="%22Fedina+A%22">Fedina A</searchLink>; Data Office Fondazione Italiana Linfomi Alessandria Italy.<br /><searchLink fieldCode="AU" term="%22Corradini+P%22">Corradini P</searchLink>; Division of Hematology and Stem Cell Transplantation Fondazione IRCCS Istituto Nazionale dei Tumori Milano Italy.; Division of Hematology and Stem Cell Transplantation University of Milan Milano Italy.<br /><searchLink fieldCode="AU" term="%22Arcaini+L%22">Arcaini L</searchLink>; Unit of Bone Marrow Transplantation and Cellular Therapies, Division of Hematology Fondazione IRCCS Policlinico San Matteo Pavia Italy.; Department of Molecular Medicine University of Pavia Pavia Italy. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101740619%22">HemaSphere</searchLink> [Hemasphere] 2026 May 21; Vol. 10 (5), pp. e70362. <i>Date of Electronic Publication: </i>2026 May 21 (<i>Print Publication: </i>2026). – Name: TypePub Label: Publication Type Group: TypPub Data: Letter – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101740619 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2572-9241 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225729241%22">25729241 </searchLink><i>NLM ISO Abbreviation: </i>Hemasphere <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42256547 |
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