Endurance exercise elicits temporal and sexual dimorphic multi-omics remodeling of liver metabolism revealed by MoTrPAC.

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Title: Endurance exercise elicits temporal and sexual dimorphic multi-omics remodeling of liver metabolism revealed by MoTrPAC.
Authors: Kelty TJ; NextGen Precision Health, University of Missouri-Columbia, Columbia, MO, USA; Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, MO, USA., Franczak E; Departments of Cell Biology and Physiology and Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA; Kansas Center for Metabolism and Obesity Research and KU Diabetes Institute, University of Kansas Medical Center, Kansas City, KS, USA., Gay NR; Department of Genetics, Stanford University, Stanford, CA, USA., Many GM; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Sagendorf TJ; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Sanford JA; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Hou Z; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA., Gaul DA; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA., Fernández FM; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA., Rekowski M; Department of Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA; Mass Spectrometry and Proteomics Core Facility, University of Kansas Medical Center, Kansas City, KS, USA., Burant CF; Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Hevener AL; Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, University of California, Los Angeles, CA, USA., Adkins JN; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Bodine S; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Lindholm ME; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA., Ortlund EA; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA., Schenk S; Department of Orthopedic Surgery, School of Medicine, University of California, San Diego, La Jolla, CA, USA., Thyfault JP; Departments of Cell Biology and Physiology and Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA; Kansas Center for Metabolism and Obesity Research and KU Diabetes Institute, University of Kansas Medical Center, Kansas City, KS, USA; Research Service, Kansas City VA Medical Center, Kansas City, MO, USA. Electronic address: jthyfault@kumc.edu., Rector RS; NextGen Precision Health, University of Missouri-Columbia, Columbia, MO, USA; Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, MO, USA; Division of Gastroenterology and Hepatology, Department of Medicine, University of Missouri, Columbia, MO, USA; Research Service, Harry S. Truman Memorial VA Medical Center, Columbia, MO, USA. Electronic address: rectors@health.missouri.edu.
Corporate Authors: MoTrPAC study group
Source: Cell reports [Cell Rep] 2026 Jun 23; Vol. 45 (6), pp. 117416. Date of Electronic Publication: 2026 Jun 08.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2211-1247
DOI:10.1016/j.celrep.2026.117416