Caspase-8 silences cell death-independent constitutive immune activation driven by tonic TNF-α.
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| Title: | Caspase-8 silences cell death-independent constitutive immune activation driven by tonic TNF-α. |
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| Authors: | Lentini G; Department of Human Pathology 'Gaetano Barresi', University of Messina, Messina, Italy., Coppolino F; Department of Human Pathology 'Gaetano Barresi', University of Messina, Messina, Italy., Famà A; Department of Human Pathology 'Gaetano Barresi', University of Messina, Messina, Italy., De Gaetano GV; Department of Human Pathology 'Gaetano Barresi', University of Messina, Messina, Italy., Grasso F; Department of Human Pathology 'Gaetano Barresi', University of Messina, Messina, Italy., Fiore L; Department of Human Pathology 'Gaetano Barresi', University of Messina, Messina, Italy., Berbiglia A; Department of Human Pathology 'Gaetano Barresi', University of Messina, Messina, Italy., Carnevale S; Humanitas Clinical and Research Center IRCCS, Rozzano, Milan, Italy., Venza I; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy., Lien E; Division of Infectious Diseases and Immunology, Program in Innate Immunity, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.; Centre of Molecular Inflammation Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Venza M; Department of Biomedical and Dental Sciences and Morphological and Functional Images, University of Messina, Messina, Italy., Jaillon S; Humanitas Clinical and Research Center IRCCS, Rozzano, Milan, Italy.; Department of Molecular Medicine, Immunology and General Pathology Unit, University of Pavia, Pavia, Italy., Teti G; Scylla Biotech Srl, Messina, Italy. gioteti@mac.com., Beninati C; Department of Human Pathology 'Gaetano Barresi', University of Messina, Messina, Italy.; Scylla Biotech Srl, Messina, Italy. |
| Source: | EMBO reports [EMBO Rep] 2026 Jul; Vol. 27 (14), pp. 4054-4078. Date of Electronic Publication: 2026 Jun 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1469-3178 |
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| DOI: | 10.1038/s44319-026-00813-5 |
