Guiding the Molnupiravir Tablet Formulation Using Physiologically Based Biopharmaceutics Modeling and Successfully Establishing Dissolution Safe Space.
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| Title: | Guiding the Molnupiravir Tablet Formulation Using Physiologically Based Biopharmaceutics Modeling and Successfully Establishing Dissolution Safe Space. |
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| Authors: | Morrow T; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA., Jarvi N; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA., Halota M; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA., Sun C; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA., Kafle P; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA., King R; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA., Okoh G; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA., Patel S; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA., Heimbach T; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA. Tycho.Heimbach@Merck.com. |
| Source: | The AAPS journal [AAPS J] 2026 Jun 08; Vol. 28 (4). Date of Electronic Publication: 2026 Jun 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42260257 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Guiding the Molnupiravir Tablet Formulation Using Physiologically Based Biopharmaceutics Modeling and Successfully Establishing Dissolution Safe Space. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Morrow+T%22">Morrow T</searchLink>; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22Jarvi+N%22">Jarvi N</searchLink>; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22Halota+M%22">Halota M</searchLink>; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22Sun+C%22">Sun C</searchLink>; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22Kafle+P%22">Kafle P</searchLink>; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22King+R%22">King R</searchLink>; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22Okoh+G%22">Okoh G</searchLink>; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22Patel+S%22">Patel S</searchLink>; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22Heimbach+T%22">Heimbach T</searchLink>; Development Sciences and Clinical Supply , MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA. Tycho.Heimbach@Merck.com. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101223209%22">The AAPS journal</searchLink> [AAPS J] 2026 Jun 08; Vol. 28 (4). <i>Date of Electronic Publication: </i>2026 Jun 08. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+of+Pharmaceutical+Scientists%22">American Association of Pharmaceutical Scientists </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101223209 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1550-7416 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215507416%22">15507416 </searchLink><i>NLM ISO Abbreviation: </i>AAPS J <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42260257 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1208/s12248-026-01249-4 Languages: – Code: eng Text: English Titles: – TitleFull: Guiding the Molnupiravir Tablet Formulation Using Physiologically Based Biopharmaceutics Modeling and Successfully Establishing Dissolution Safe Space. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Morrow T – PersonEntity: Name: NameFull: Jarvi N – PersonEntity: Name: NameFull: Halota M – PersonEntity: Name: NameFull: Sun C – PersonEntity: Name: NameFull: Kafle P – PersonEntity: Name: NameFull: King R – PersonEntity: Name: NameFull: Okoh G – PersonEntity: Name: NameFull: Patel S – PersonEntity: Name: NameFull: Heimbach T IsPartOfRelationships: – BibEntity: Dates: – D: 08 M: 06 Text: 2026 Jun 08 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1550-7416 Numbering: – Type: volume Value: 28 – Type: issue Value: 4 Titles: – TitleFull: The AAPS journal Type: main |
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