APOL1-risk alleles modulate T-cell receptor signaling to promote allograft rejection.

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Title: APOL1-risk alleles modulate T-cell receptor signaling to promote allograft rejection.
Authors: Pell J; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America., Tanvir EM; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America., Sun Z; Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, United States of America., Chernova I; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America., Reghuvaran A; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America., Nagata S; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America., Guerra MT; Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, United States of America., Choi J; Transplant Research Center, Division of Renal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, United States of America., Al Chaar S; Transplant Research Center, Division of Renal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, United States of America., Mizuno H; Transplant Research Center, Division of Renal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, United States of America., Dong K; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America., Tian X; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America., Ishibe R; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America., Franchin B; Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, United States of America., Cravedi P; Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, United States of America., Kumar A; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America., Barsotti G; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America., Shi H; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America., De Kumar B; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America., Smithson S; Division of Nephrology, Washington University, St. Louis, United States of America., Song W; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America., He JC; Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, United States of America., Chong AS; Department of Surgery, The University of Chicago, Chicago, United States of America., Pober JS; Department of Immunobiology, Yale University School of Medicine, New Haven, United States of America., Somlo S; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America., Gibson IW; Department of Pathology, University of Manitoba, Winnipeg, Canada., Popik W; Center for AIDS Health Disparities Research, Department of Internal Medicin, Meharry Medical College, Nashville, United States of America., Zhang Z; Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, United States of America., Craft J; Department of Immunobiology, Yale University School of Medicine, New Haven, United States of America., Azzi J; Transplant Research Center, Division of Renal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, United States of America., Murakami N; Transplant Research Center, Division of Renal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, United States of America., Ishibe S; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America., Heeger PS; Cedars-Sinai Medical Center, Los Angeles, United States of America., Menon MC; Section of Nephrology, Yale University School of Medicine, New Haven, United States of America.
Source: The Journal of clinical investigation [J Clin Invest] 2026 Jun 09. Date of Electronic Publication: 2026 Jun 09.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1558-8238
DOI:10.1172/JCI193173