GBP1 recruitment to actin-rich pedestals of extracellular Gram-negative bacteria promotes pyroptosis.
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| Title: | GBP1 recruitment to actin-rich pedestals of extracellular Gram-negative bacteria promotes pyroptosis. |
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| Authors: | Bennison DJ; Department of Infectious Disease, Imperial College London, London, UK., Chaudhary I; Department of Infectious Disease, Imperial College London, London, UK.; Indian Institute of Science Education and Research, Pune, India., Chaudhuri D; Department of Infectious Disease, Imperial College London, London, UK.; Department of Developmental Biology & Genetics, Indian Institute of Science, Bengaluru, India., Wong JCN; Department of Infectious Disease, Imperial College London, London, UK., Punwatkar A; Department of Infectious Disease, Imperial College London, London, UK., Biswas P; Department of Life Sciences, Imperial College London, London, UK., Stephenson M; Department of Infectious Disease, Imperial College London, London, UK., Zhong Q; Department of Infectious Disease, Imperial College London, London, UK., Kallemeijn WW; The Francis Crick Institute, London, UK.; Department of Chemistry, Imperial College London, London, UK., Guenot M; Department of Life Sciences, Imperial College London, London, UK., Koigi S; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.; NIHR Imperial BRC Organoid Facility, Imperial College London, London, UK., Papp D; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.; NIHR Imperial BRC Organoid Facility, Imperial College London, London, UK., Thomas JP; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.; UKRI MRC Laboratory of Medical Sciences, Hammersmith Hospital Campus, London, UK., Dixit D; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK., Korcsmaros T; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.; NIHR Imperial BRC Organoid Facility, Imperial College London, London, UK., Talman AM; MIVEGEC, University of Montpellier, IRD, CNRS, Montpellier, France., Frickel EM; Department of Microbiology and Molecular Medicine, University of Geneva, Geneva, Switzerland., Tate EW; The Francis Crick Institute, London, UK.; Department of Chemistry, Imperial College London, London, UK., Visweswariah SS; Department of Developmental Biology & Genetics, Indian Institute of Science, Bengaluru, India.; Department of Life Sciences, Imperial College London, London, UK., Frankel G; Department of Life Sciences, Imperial College London, London, UK., Shenoy AR; Department of Infectious Disease, Imperial College London, London, UK. a.shenoy@imperial.ac.uk. |
| Source: | The EMBO journal [EMBO J] 2026 Jul; Vol. 45 (14), pp. 5046-5078. Date of Electronic Publication: 2026 Jun 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1460-2075 |
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| DOI: | 10.1038/s44318-026-00830-z |