Repurposing doxycycline as an adjunct to sitagliptin in type 2 diabetes mellitus: a randomized controlled study on glycemic, inflammatory, and cardiometabolic outcomes.
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| Title: | Repurposing doxycycline as an adjunct to sitagliptin in type 2 diabetes mellitus: a randomized controlled study on glycemic, inflammatory, and cardiometabolic outcomes. |
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| Authors: | El-Khateeb E; Clinical Pharmacy Department, Faculty of Pharmacy, Tanta University, Tanta, Egypt., Khrieba MO; Pharmacy Practice Department, Faculty of Pharmacy, Horus University, New Damietta, Egypt.; Pharmacy Practice Department, Faculty of Pharmacy, East Port Said National University, Port Said, Egypt., Badawoud AM; Department of Pharmacy Practice, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, 11671, Saudi Arabia. ambadawoud@pnu.edu.sa., Morsy AA; Department of Clinical Pharmacy, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza, Egypt., El-Hanafy AA; Department of Basic Dental and Medical Sciences, Faculty of Dentistry, Mutah University, Karak, Jordan.; Department of Medical Biochemistry & Molecular Biology, Faculty of Medicine, Mansoura University, Mansoura, Egypt., Hamza E; Department of Biochemistry, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia., Habba E; Tropical Medicine and Infectious Diseases Department, Faculty of Medicine, Tanta University, Tanta, Egypt., El-Hanafy DA; Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt., Eltantawy N; Clinical Pharmacy and Pharmacy Practice Department, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo, Egypt., Al-Dhelaan RA; Department of Biochemistry, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia., Radwan KH; Biochemistry Department, Horus University-Egypt, New Damietta, Egypt., El-Sayed AA; Department of Pharmacy Practice, Faculty of Pharmacy, Arish Branch, Sinai University, Arish, Egypt., Eladaroussay MM; Histology and Cell Biology Department, Faculty of Medicine, Horus University-Egypt, New Damietta, Egypt., Rizk KAK; Histology and Cell Biology Department, Faculty of Medicine, Horus University-Egypt, New Damietta, Egypt., Ebrahim MHE; Histology and Cell Biology Department, Faculty of Medicine, Horus University-Egypt, New Damietta, Egypt., Abd Elhameed AG; Pharmacology and Toxicology Department, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.; Pharmacology and Biochemistry Department (Pharmacology Speciality), Faculty of Pharmacy, Horus University, New Damietta, Egypt., Erfan IA; Pharmacology and Biochemistry Department (Biochemistry Specialty), Faculty of Pharmacy, Horus University, New Damietta, Egypt., Elkhodary NM; Department of Clinical Pharmacy, Faculty of Pharmacy, Kafrelsheikh University, Kafr El-Sheikh, 33516, Egypt., Elshorbagi N; Pharmacology and Toxicology Department, Faculty of Pharmacy, East Kantara Branch, Sinai University, Ismailia, 41636, Egypt., Sami HM; Department of Pharmacy Practice, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Dewidar SA; Clinical Pharmacy and Pharmacy Practice Department, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt., Mahdy MA; Internal Medicine Department, Gastroenterology and Hepatology Unit, Assiut University, Assiut, Egypt., Zakaria H; Clinical Pharmacy and Pharmacy Practice Department, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt. |
| Source: | Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 Jun 11. Date of Electronic Publication: 2026 Jun 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42271067 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Repurposing doxycycline as an adjunct to sitagliptin in type 2 diabetes mellitus: a randomized controlled study on glycemic, inflammatory, and cardiometabolic outcomes. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22El-Khateeb+E%22">El-Khateeb E</searchLink>; Clinical Pharmacy Department, Faculty of Pharmacy, Tanta University, Tanta, Egypt.<br /><searchLink fieldCode="AU" term="%22Khrieba+MO%22">Khrieba MO</searchLink>; Pharmacy Practice Department, Faculty of Pharmacy, Horus University, New Damietta, Egypt.; Pharmacy Practice Department, Faculty of Pharmacy, East Port Said National University, Port Said, Egypt.<br /><searchLink fieldCode="AU" term="%22Badawoud+AM%22">Badawoud AM</searchLink>; Department of Pharmacy Practice, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, 11671, Saudi Arabia. ambadawoud@pnu.edu.sa.<br /><searchLink fieldCode="AU" term="%22Morsy+AA%22">Morsy AA</searchLink>; Department of Clinical Pharmacy, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Hanafy+AA%22">El-Hanafy AA</searchLink>; Department of Basic Dental and Medical Sciences, Faculty of Dentistry, Mutah University, Karak, Jordan.; Department of Medical Biochemistry & Molecular Biology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.<br /><searchLink fieldCode="AU" term="%22Hamza+E%22">Hamza E</searchLink>; Department of Biochemistry, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Habba+E%22">Habba E</searchLink>; Tropical Medicine and Infectious Diseases Department, Faculty of Medicine, Tanta University, Tanta, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Hanafy+DA%22">El-Hanafy DA</searchLink>; Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.<br /><searchLink fieldCode="AU" term="%22Eltantawy+N%22">Eltantawy N</searchLink>; Clinical Pharmacy and Pharmacy Practice Department, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Al-Dhelaan+RA%22">Al-Dhelaan RA</searchLink>; Department of Biochemistry, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Radwan+KH%22">Radwan KH</searchLink>; Biochemistry Department, Horus University-Egypt, New Damietta, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Sayed+AA%22">El-Sayed AA</searchLink>; Department of Pharmacy Practice, Faculty of Pharmacy, Arish Branch, Sinai University, Arish, Egypt.<br /><searchLink fieldCode="AU" term="%22Eladaroussay+MM%22">Eladaroussay MM</searchLink>; Histology and Cell Biology Department, Faculty of Medicine, Horus University-Egypt, New Damietta, Egypt.<br /><searchLink fieldCode="AU" term="%22Rizk+KAK%22">Rizk KAK</searchLink>; Histology and Cell Biology Department, Faculty of Medicine, Horus University-Egypt, New Damietta, Egypt.<br /><searchLink fieldCode="AU" term="%22Ebrahim+MHE%22">Ebrahim MHE</searchLink>; Histology and Cell Biology Department, Faculty of Medicine, Horus University-Egypt, New Damietta, Egypt.<br /><searchLink fieldCode="AU" term="%22Abd+Elhameed+AG%22">Abd Elhameed AG</searchLink>; Pharmacology and Toxicology Department, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.; Pharmacology and Biochemistry Department (Pharmacology Speciality), Faculty of Pharmacy, Horus University, New Damietta, Egypt.<br /><searchLink fieldCode="AU" term="%22Erfan+IA%22">Erfan IA</searchLink>; Pharmacology and Biochemistry Department (Biochemistry Specialty), Faculty of Pharmacy, Horus University, New Damietta, Egypt.<br /><searchLink fieldCode="AU" term="%22Elkhodary+NM%22">Elkhodary NM</searchLink>; Department of Clinical Pharmacy, Faculty of Pharmacy, Kafrelsheikh University, Kafr El-Sheikh, 33516, Egypt.<br /><searchLink fieldCode="AU" term="%22Elshorbagi+N%22">Elshorbagi N</searchLink>; Pharmacology and Toxicology Department, Faculty of Pharmacy, East Kantara Branch, Sinai University, Ismailia, 41636, Egypt.<br /><searchLink fieldCode="AU" term="%22Sami+HM%22">Sami HM</searchLink>; Department of Pharmacy Practice, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt.<br /><searchLink fieldCode="AU" term="%22Dewidar+SA%22">Dewidar SA</searchLink>; Clinical Pharmacy and Pharmacy Practice Department, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.<br /><searchLink fieldCode="AU" term="%22Mahdy+MA%22">Mahdy MA</searchLink>; Internal Medicine Department, Gastroenterology and Hepatology Unit, Assiut University, Assiut, Egypt.<br /><searchLink fieldCode="AU" term="%22Zakaria+H%22">Zakaria H</searchLink>; Clinical Pharmacy and Pharmacy Practice Department, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220326264%22">Naunyn-Schmiedeberg's archives of pharmacology</searchLink> [Naunyn Schmiedebergs Arch Pharmacol] 2026 Jun 11. <i>Date of Electronic Publication: </i>2026 Jun 11. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0326264 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1912 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200281298%22">00281298 </searchLink><i>NLM ISO Abbreviation: </i>Naunyn Schmiedebergs Arch Pharmacol <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00210-026-05510-7 Languages: – Code: eng Text: English Titles: – TitleFull: Repurposing doxycycline as an adjunct to sitagliptin in type 2 diabetes mellitus: a randomized controlled study on glycemic, inflammatory, and cardiometabolic outcomes. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: El-Khateeb E – PersonEntity: Name: NameFull: Khrieba MO – PersonEntity: Name: NameFull: Badawoud AM – PersonEntity: Name: NameFull: Morsy AA – PersonEntity: Name: NameFull: El-Hanafy AA – PersonEntity: Name: NameFull: Hamza E – PersonEntity: Name: NameFull: Habba E – PersonEntity: Name: NameFull: El-Hanafy DA – PersonEntity: Name: NameFull: Eltantawy N – PersonEntity: Name: NameFull: Al-Dhelaan RA – PersonEntity: Name: NameFull: Radwan KH – PersonEntity: Name: NameFull: El-Sayed AA – PersonEntity: Name: NameFull: Eladaroussay MM – PersonEntity: Name: NameFull: Rizk KAK – PersonEntity: Name: NameFull: Ebrahim MHE – PersonEntity: Name: NameFull: Abd Elhameed AG – PersonEntity: Name: NameFull: Erfan IA – PersonEntity: Name: NameFull: Elkhodary NM – PersonEntity: Name: NameFull: Elshorbagi N – PersonEntity: Name: NameFull: Sami HM – PersonEntity: Name: NameFull: Dewidar SA – PersonEntity: Name: NameFull: Mahdy MA – PersonEntity: Name: NameFull: Zakaria H IsPartOfRelationships: – BibEntity: Dates: – D: 11 M: 06 Text: 2026 Jun 11 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1432-1912 Titles: – TitleFull: Naunyn-Schmiedeberg's archives of pharmacology Type: main |
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