The promyelocytic leukemia PML protein coordinates immune evasion in triple-negative breast cancer via independent and converging mechanisms.

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Title: The promyelocytic leukemia PML protein coordinates immune evasion in triple-negative breast cancer via independent and converging mechanisms.
Authors: Uggè M; Mechanisms of Non-oncogene Addiction in Cancer Unit, Comprehensive Cancer Center, IRCCS Ospedale San Raffaele, Milan, Italy., Fracassi C; Mechanisms of Non-oncogene Addiction in Cancer Unit, Comprehensive Cancer Center, IRCCS Ospedale San Raffaele, Milan, Italy.; Institute of Human Genetics (IGH), University of Montpellier, CNRS, Montpellier, France., Tascini AS; Center for Omics Sciences COSR, IRCCS Ospedale San Raffaele, Milan, Italy., Giansanti V; Center for Omics Sciences COSR, IRCCS Ospedale San Raffaele, Milan, Italy., Genova F; Center for Omics Sciences COSR, IRCCS Ospedale San Raffaele, Milan, Italy., Dugo M; Department of Medical Oncology, IRCCS Ospedale San Raffaele, Milan, Italy., Giannese F; Center for Omics Sciences COSR, IRCCS Ospedale San Raffaele, Milan, Italy., Basso V; Lymphocyte Activation Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milan, Italy., Ghirardi C; Department of Molecular Oncology, European Institute of Oncology (IEO) IRCCS, Milan, Italy., Smart CE; Pathology Unit, Università Vita-Salute San Raffaele, Milan, Italy.; Cairns and Hinterland Hospital and Health Service, Queensland Health, Cairns, QLD, Australia., Doglioni C; Pathology Unit, Università Vita-Salute San Raffaele, Milan, Italy., Casorati G; Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milan, Italy., Dellabona P; Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milan, Italy., Zambelli S; Department of Medical Oncology, IRCCS Ospedale San Raffaele, Milan, Italy., Servitja Tormo S; GEICAM Spanish Breast Cancer Group, Madrid, Spain.; Oncology Department, Hospital del Mar, Barcelona, Spain., Cruz Jurado J; GEICAM Spanish Breast Cancer Group, Madrid, Spain.; Oncology Department, Hospital Universitario de Canarias, Tenerife, Spain., Gianni L; Fondazione Michelangelo, Milan, Italy., Bonaldi T; Department of Molecular Oncology, European Institute of Oncology (IEO) IRCCS, Milan, Italy.; Department of Oncology and Haemato-Oncology, University of Milan, Milan, Italy., Agresti A; Mechanisms of Non-oncogene Addiction in Cancer Unit, Comprehensive Cancer Center, IRCCS Ospedale San Raffaele, Milan, Italy., Mondino A; Lymphocyte Activation Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milan, Italy., Bianchini G; Department of Medical Oncology, IRCCS Ospedale San Raffaele, Milan, Italy.; Università Vita-Salute San Raffaele, Milan, Italy., Bernardi R; Mechanisms of Non-oncogene Addiction in Cancer Unit, Comprehensive Cancer Center, IRCCS Ospedale San Raffaele, Milan, Italy. bernardi.rosa@hsr.it.
Source: Cell death and differentiation [Cell Death Differ] 2026 Jun 10. Date of Electronic Publication: 2026 Jun 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5403
DOI:10.1038/s41418-026-01781-y