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S100A10-ANXA2 tetramer inhibition hampers hepatic stellate cell activation in human MASLD organoids.

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Title: S100A10-ANXA2 tetramer inhibition hampers hepatic stellate cell activation in human MASLD organoids.
Authors: Türkal M; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland., Maeder C; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland., Correia de Sousa M; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland., Fournier M; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland., El-Harane S; Department of Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Gjorgjieva M; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland., Foti M; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland., Maecher P; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland. Pierre.maechler@unige.ch.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland. Pierre.maechler@unige.ch., Delangre E; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland. Etienne.delangre@unige.ch.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland. Etienne.delangre@unige.ch.
Source: EMBO molecular medicine [EMBO Mol Med] 2026 Jul; Vol. 18 (7), pp. 2920-2945. Date of Electronic Publication: 2026 Jun 10.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
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  Data: S100A10-ANXA2 tetramer inhibition hampers hepatic stellate cell activation in human MASLD organoids.
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  Data: <searchLink fieldCode="AU" term="%22Türkal+M%22">Türkal M</searchLink>; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Maeder+C%22">Maeder C</searchLink>; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Correia+de+Sousa+M%22">Correia de Sousa M</searchLink>; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Fournier+M%22">Fournier M</searchLink>; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22El-Harane+S%22">El-Harane S</searchLink>; Department of Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gjorgjieva+M%22">Gjorgjieva M</searchLink>; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Foti+M%22">Foti M</searchLink>; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Maecher+P%22">Maecher P</searchLink>; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland. Pierre.maechler@unige.ch.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland. Pierre.maechler@unige.ch.<br /><searchLink fieldCode="AU" term="%22Delangre+E%22">Delangre E</searchLink>; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland. Etienne.delangre@unige.ch.; Faculty of Medicine, Diabetes Center, University of Geneva, Geneva, Switzerland. Etienne.delangre@unige.ch.
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  Data: <searchLink fieldCode="JN" term="%22101487380%22">EMBO molecular medicine</searchLink> [EMBO Mol Med] 2026 Jul; Vol. 18 (7), pp. 2920-2945. <i>Date of Electronic Publication: </i>2026 Jun 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101487380 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-4684 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217574676%22">17574676 </searchLink><i>NLM ISO Abbreviation: </i>EMBO Mol Med <i>Subsets: </i>MEDLINE
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              Text: 2026 Jul
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