Antibody format matters: A comparative analysis of VHH and scFv domains reveals superior in vivo CAR T cell function with VHH domains.
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| Title: | Antibody format matters: A comparative analysis of VHH and scFv domains reveals superior in vivo CAR T cell function with VHH domains. |
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| Authors: | Kinna A; Autolus Therapeutics Plc, London W12 7FP, UK., Datta P; Autolus Therapeutics Plc, London W12 7FP, UK., Bughda R; Autolus Therapeutics Plc, London W12 7FP, UK., Parekh F; Autolus Therapeutics Plc, London W12 7FP, UK., Robson M; Autolus Therapeutics Plc, London W12 7FP, UK., Jha R; Autolus Therapeutics Plc, London W12 7FP, UK., Wu P; Autolus Therapeutics Plc, London W12 7FP, UK., Scott I; Autolus Therapeutics Plc, London W12 7FP, UK., Hogben E; Autolus Therapeutics Plc, London W12 7FP, UK., Amin O; Autolus Therapeutics Plc, London W12 7FP, UK., Weng-Kit Cheung G; Developmental Biology and Cancer Department, The Cancer Institute, Paul O'Gorman Building, University College London, London WC1E 6DD, UK., Hazelton W; Developmental Biology and Cancer Department, The Cancer Institute, Paul O'Gorman Building, University College London, London WC1E 6DD, UK., Akbar Z; Autolus Therapeutics Plc, London W12 7FP, UK., Lamb K; Autolus Therapeutics Plc, London W12 7FP, UK., Macken E; Autolus Therapeutics Plc, London W12 7FP, UK., Allen C; Autolus Therapeutics Plc, London W12 7FP, UK., Panovska S; Autolus Therapeutics Plc, London W12 7FP, UK., Hogan L; Autolus Therapeutics Plc, London W12 7FP, UK., El-Kholy M; Autolus Therapeutics Plc, London W12 7FP, UK., Shrestha R; Autolus Therapeutics Plc, London W12 7FP, UK., Popplewell J; Carterra Inc, Salt Lake City, UT 84103, USA., Kokalaki E; Autolus Therapeutics Plc, London W12 7FP, UK., Sillibourne J; Autolus Therapeutics Plc, London W12 7FP, UK., Thomas S; Autolus Therapeutics Plc, London W12 7FP, UK., Onuoha S; Autolus Therapeutics Plc, London W12 7FP, UK., Ferrari M; Autolus Therapeutics Plc, London W12 7FP, UK., Pule M; Autolus Therapeutics Plc, London W12 7FP, UK; Developmental Biology and Cancer Department, The Cancer Institute, Paul O'Gorman Building, University College London, London WC1E 6DD, UK. Electronic address: m.pule@autolus.com. |
| Source: | Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2026 Jun 10. Date of Electronic Publication: 2026 Jun 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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