FEMA-Long: Modeling unstructured covariances for discovery of time-dependent effects in large-scale longitudinal datasets.
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| Title: | FEMA-Long: Modeling unstructured covariances for discovery of time-dependent effects in large-scale longitudinal datasets. |
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| Authors: | Parekh P; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway.; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, California, United States of America., Parker N; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Pecheva D; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, California, United States of America., Frei E; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Vaudel M; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Computational Biology Unit, Department of Informatics, University of Bergen, Bergen, Norway.; Department of Genetics and Bioinformatics, Norwegian Institute of Public Health, Bergen, Norway., Smith DM; Center for Human Development, University of California San Diego, La Jolla, California, United States of America.; Medical Scientist Training Program, University of California San Diego, La Jolla, California, United States of America., Rigby A; Neuroscience Graduate Program, University of California San Diego, La Jolla, California, United States of America., Jahołkowski P; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Sønderby IE; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway.; Department of Medical Genetics, Oslo University Hospital & University of Oslo, Oslo, Norway., Birkenæs V; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway.; PsychGen Center for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway., Bakken NR; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway.; PsychGen Center for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway., Fan CC; Center for Population Neuroscience and Genetics, Laureate Institute for Brain Research, Tulsa, Oklahoma, United States of America., Makowski C; Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, California, United States of America., Kopal J; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Loughnan R; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, California, United States of America.; Population Neuroscience and Genetics Lab, University of California San Diego, La Jolla, California, United States of America., Hagler DJ Jr; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, California, United States of America., van der Meer D; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Johansson S; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Pediatrics and Adolescents, Haukeland University Hospital, Bergen, Norway., Njølstad PR; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Pediatrics and Adolescents, Haukeland University Hospital, Bergen, Norway., Jernigan TL; Department of Radiology, School of Medicine, University of California San Diego, La Jolla, California, United States of America.; Center for Human Development, University of California San Diego, La Jolla, California, United States of America.; Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, California, United States of America.; Department of Cognitive Science, University of California San Diego, La Jolla, California, United States of America., Thompson WK; Center for Population Neuroscience and Genetics, Laureate Institute for Brain Research, Tulsa, Oklahoma, United States of America., Frei O; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway.; Department of Pharmacy, Section for Pharmacology and Pharmaceutical Biosciences, University of Oslo, Oslo, Norway., Shadrin AA; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Nichols TE; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.; Oxford Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom., Andreassen OA; Centre for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Dale AM; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, California, United States of America.; University of California San Diego, La Jolla, California, United States of America.; University of Oslo, Oslo, Norway. |
| Source: | PLoS genetics [PLoS Genet] 2026 Jun 11; Vol. 22 (6), pp. e1012184. Date of Electronic Publication: 2026 Jun 11 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1553-7404 |
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| DOI: | 10.1371/journal.pgen.1012184 |
