Dihydrotanshinone I as a novel signal transducer and activator of transcription 3 inhibitor for glioblastoma treatment.

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Title: Dihydrotanshinone I as a novel signal transducer and activator of transcription 3 inhibitor for glioblastoma treatment.
Authors: Cheng KW; Department of Medical Research Center, Shaoxing People's Hospital, School of Medicine, ShaoXing University, Shaoxing, 312000, China.; Department of Neurology, Shaoxing People's Hospital, Shaoxing, 312000, China., Zhou SJ; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; National Key Laboratory of Advanced Drug Delivery and Release Systems, Zhejiang University, Hangzhou, 310058, China., Zeng J; Department of Neurology, Shaoxing People's Hospital, Shaoxing, 312000, China.; School of Medicine, ShaoXing University, Shaoxing, 312000, China., Zhang YR; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; National Key Laboratory of Advanced Drug Delivery and Release Systems, Zhejiang University, Hangzhou, 310058, China., Jin BQ; School of Medicine, ShaoXing University, Shaoxing, 312000, China., Wang P; Department of Blood Transfusion, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing, 312000, China., He LY; Department of Traditional Chinese Medicine, Shaoxing People's Hospital, Zhejiang University Shaoxing Hospital, Shaoxing, China., Qi XC; Department of Neurosurgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310024, China., Liu XD; Bioengineering College of Chongqing University, Chongqing, 400030, China. liuxubio@126.com., Yu LS; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. yuls@zju.edu.cn.; National Key Laboratory of Advanced Drug Delivery and Release Systems, Zhejiang University, Hangzhou, 310058, China. yuls@zju.edu.cn., Zhang YX; Department of Neurology, Shaoxing People's Hospital, Shaoxing, 312000, China. auwxf01@163.com.; School of Medicine, ShaoXing University, Shaoxing, 312000, China. auwxf01@163.com.; State Key Laboratory of Neurology and Oncology Drug Development, Jiangsu Simcere Pharmaceutical Co. Ltd., 699-18 Xuan Wi Avemue, Nanjing, Jiangsu, 210042, China. auwxf01@163.com.
Source: Journal of translational medicine [J Transl Med] 2026 Jun 11. Date of Electronic Publication: 2026 Jun 11.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1479-5876
DOI:10.1186/s12967-026-08385-7