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Dihydrotanshinone I as a novel signal transducer and activator of transcription 3 inhibitor for glioblastoma treatment.

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Title: Dihydrotanshinone I as a novel signal transducer and activator of transcription 3 inhibitor for glioblastoma treatment.
Authors: Cheng KW; Department of Medical Research Center, Shaoxing People's Hospital, School of Medicine, ShaoXing University, Shaoxing, 312000, China.; Department of Neurology, Shaoxing People's Hospital, Shaoxing, 312000, China., Zhou SJ; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; National Key Laboratory of Advanced Drug Delivery and Release Systems, Zhejiang University, Hangzhou, 310058, China., Zeng J; Department of Neurology, Shaoxing People's Hospital, Shaoxing, 312000, China.; School of Medicine, ShaoXing University, Shaoxing, 312000, China., Zhang YR; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; National Key Laboratory of Advanced Drug Delivery and Release Systems, Zhejiang University, Hangzhou, 310058, China., Jin BQ; School of Medicine, ShaoXing University, Shaoxing, 312000, China., Wang P; Department of Blood Transfusion, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing, 312000, China., He LY; Department of Traditional Chinese Medicine, Shaoxing People's Hospital, Zhejiang University Shaoxing Hospital, Shaoxing, China., Qi XC; Department of Neurosurgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310024, China., Liu XD; Bioengineering College of Chongqing University, Chongqing, 400030, China. liuxubio@126.com., Yu LS; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. yuls@zju.edu.cn.; National Key Laboratory of Advanced Drug Delivery and Release Systems, Zhejiang University, Hangzhou, 310058, China. yuls@zju.edu.cn., Zhang YX; Department of Neurology, Shaoxing People's Hospital, Shaoxing, 312000, China. auwxf01@163.com.; School of Medicine, ShaoXing University, Shaoxing, 312000, China. auwxf01@163.com.; State Key Laboratory of Neurology and Oncology Drug Development, Jiangsu Simcere Pharmaceutical Co. Ltd., 699-18 Xuan Wi Avemue, Nanjing, Jiangsu, 210042, China. auwxf01@163.com.
Source: Journal of translational medicine [J Transl Med] 2026 Jun 11. Date of Electronic Publication: 2026 Jun 11.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dihydrotanshinone I as a novel signal transducer and activator of transcription 3 inhibitor for glioblastoma treatment.
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  Data: <searchLink fieldCode="AU" term="%22Cheng+KW%22">Cheng KW</searchLink>; Department of Medical Research Center, Shaoxing People's Hospital, School of Medicine, ShaoXing University, Shaoxing, 312000, China.; Department of Neurology, Shaoxing People's Hospital, Shaoxing, 312000, China.<br /><searchLink fieldCode="AU" term="%22Zhou+SJ%22">Zhou SJ</searchLink>; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; National Key Laboratory of Advanced Drug Delivery and Release Systems, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Zeng+J%22">Zeng J</searchLink>; Department of Neurology, Shaoxing People's Hospital, Shaoxing, 312000, China.; School of Medicine, ShaoXing University, Shaoxing, 312000, China.<br /><searchLink fieldCode="AU" term="%22Zhang+YR%22">Zhang YR</searchLink>; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; National Key Laboratory of Advanced Drug Delivery and Release Systems, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Jin+BQ%22">Jin BQ</searchLink>; School of Medicine, ShaoXing University, Shaoxing, 312000, China.<br /><searchLink fieldCode="AU" term="%22Wang+P%22">Wang P</searchLink>; Department of Blood Transfusion, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing, 312000, China.<br /><searchLink fieldCode="AU" term="%22He+LY%22">He LY</searchLink>; Department of Traditional Chinese Medicine, Shaoxing People's Hospital, Zhejiang University Shaoxing Hospital, Shaoxing, China.<br /><searchLink fieldCode="AU" term="%22Qi+XC%22">Qi XC</searchLink>; Department of Neurosurgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310024, China.<br /><searchLink fieldCode="AU" term="%22Liu+XD%22">Liu XD</searchLink>; Bioengineering College of Chongqing University, Chongqing, 400030, China. liuxubio@126.com.<br /><searchLink fieldCode="AU" term="%22Yu+LS%22">Yu LS</searchLink>; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. yuls@zju.edu.cn.; National Key Laboratory of Advanced Drug Delivery and Release Systems, Zhejiang University, Hangzhou, 310058, China. yuls@zju.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+YX%22">Zhang YX</searchLink>; Department of Neurology, Shaoxing People's Hospital, Shaoxing, 312000, China. auwxf01@163.com.; School of Medicine, ShaoXing University, Shaoxing, 312000, China. auwxf01@163.com.; State Key Laboratory of Neurology and Oncology Drug Development, Jiangsu Simcere Pharmaceutical Co. Ltd., 699-18 Xuan Wi Avemue, Nanjing, Jiangsu, 210042, China. auwxf01@163.com.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190741 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-5876 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214795876%22">14795876 </searchLink><i>NLM ISO Abbreviation: </i>J Transl Med <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12967-026-08385-7
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            – D: 11
              M: 06
              Text: 2026 Jun 11
              Type: published
              Y: 2026
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