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Multicomponent Stapling of Glucagon-Like Peptide-1 Enables Receptor-Guided PROTAC Delivery.

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Title: Multicomponent Stapling of Glucagon-Like Peptide-1 Enables Receptor-Guided PROTAC Delivery.
Authors: Venne JL; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.; AstraZeneca Plc, Cambridge Biomedical Campus 1 Francis Crick Avenue, Cambridge, UK., Krajcovicova S; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.; Department of Organic Chemistry, Palacky University Olomouc, Olomouc, Czech Republic., Davies G; AstraZeneca Plc, Cambridge Biomedical Campus 1 Francis Crick Avenue, Cambridge, UK., Bolt H; AstraZeneca Plc, Cambridge Biomedical Campus 1 Francis Crick Avenue, Cambridge, UK., Revell J; AstraZeneca Plc, Cambridge Biomedical Campus 1 Francis Crick Avenue, Cambridge, UK., Spring DR; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.
Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2026 Jun 12, pp. e9595531. Date of Electronic Publication: 2026 Jun 12.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Venne+JL%22">Venne JL</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.; AstraZeneca Plc, Cambridge Biomedical Campus 1 Francis Crick Avenue, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Krajcovicova+S%22">Krajcovicova S</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.; Department of Organic Chemistry, Palacky University Olomouc, Olomouc, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Davies+G%22">Davies G</searchLink>; AstraZeneca Plc, Cambridge Biomedical Campus 1 Francis Crick Avenue, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Bolt+H%22">Bolt H</searchLink>; AstraZeneca Plc, Cambridge Biomedical Campus 1 Francis Crick Avenue, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Revell+J%22">Revell J</searchLink>; AstraZeneca Plc, Cambridge Biomedical Campus 1 Francis Crick Avenue, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Spring+DR%22">Spring DR</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.
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              Text: 2026 Jun 12
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