Fluorogenic/chromogenic enzyme substrates constructed around the 2-amino-7-nitrofluorene core structure for the detection of aminopeptidase activities in clinically important microorganisms.

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Title: Fluorogenic/chromogenic enzyme substrates constructed around the 2-amino-7-nitrofluorene core structure for the detection of aminopeptidase activities in clinically important microorganisms.
Authors: Chalansonnet V; Research & Development Microbiology, bioMérieux SA, 3 route de Port Michaud, 38390 La Balme-les-Grottes, France., Marsh CE; School of Geography & Natural Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK., Orenga S; Research & Development Microbiology, bioMérieux SA, 3 route de Port Michaud, 38390 La Balme-les-Grottes, France., Perry JD; Department of Microbiology, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK., Stanforth SP; School of Geography & Natural Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK., Sykes HE; School of Geography & Natural Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK., Truong TV; School of Pharmacy & Pharmaceutical Sciences, University of Sunderland, SR1 3SD, UK., Turnbull G; School of Geography & Natural Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK. Electronic address: g.turnbull@northumbria.ac.uk., Twist A; School of Geography & Natural Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK., Zaytsev A; School of Geography & Natural Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.
Source: Bioorganic chemistry [Bioorg Chem] 2026 Jun 09; Vol. 180, pp. 110093. Date of Electronic Publication: 2026 Jun 09.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1090-2120
DOI:10.1016/j.bioorg.2026.110093