Enrichment of mutated DNA enables ultra-sensitive ctDNA detection in NSCLC using shallow targeted sequencing.
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| Title: | Enrichment of mutated DNA enables ultra-sensitive ctDNA detection in NSCLC using shallow targeted sequencing. |
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| Authors: | Labrousse P; 35 Gatehouse Drive, Waltham, MA, 02451, USA. paul.labrousse@astrazeneca.com., Russell H; 35 Gatehouse Drive, Waltham, MA, 02451, USA., Stetson D; 35 Gatehouse Drive, Waltham, MA, 02451, USA., Powalowska-Pickton PK; Biofidelity Ltd, Cambridge, CB4 0WN, UK., Anton KA; Biofidelity Ltd, Cambridge, CB4 0WN, UK., Litovchenko M; Biofidelity Ltd, Cambridge, CB4 0WN, UK., Lowy-Gallego E; Biofidelity Ltd, Cambridge, CB4 0WN, UK., Lovell A; Biofidelity Ltd, Cambridge, CB4 0WN, UK., Hackinger S; Biofidelity Ltd, Cambridge, CB4 0WN, UK., Stolarek-Januszkiewicz M; Biofidelity Ltd, Cambridge, CB4 0WN, UK., Balmforth BW; Biofidelity Ltd, Cambridge, CB4 0WN, UK., Hadfield J; AstraZeneca, Cambridge, CB2 0AA, UK. |
| Source: | Scientific reports [Sci Rep] 2026 Jun 13. Date of Electronic Publication: 2026 Jun 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-026-57421-5 |
