Efficacy and safety of eptinezumab in adults with chronic migraine and medication-overuse headache who also received patient education: 24-week results of the randomized RESOLUTION trial.

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Title: Efficacy and safety of eptinezumab in adults with chronic migraine and medication-overuse headache who also received patient education: 24-week results of the randomized RESOLUTION trial.
Authors: Schytz HW; Danish Headache Center, Department of Neurology, Rigshospitalet-Glostrup, University of Copenhagen, Copenhagen, Denmark. henrik.winther.schytz.01@regionh.dk., Jensen RH; Danish Headache Center, Department of Neurology, Rigshospitalet-Glostrup, University of Copenhagen, Copenhagen, Denmark., Lundqvist C; Departments of Neurology and Health Services Research, Akershus University Hospital, Lørenskog, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Tassorelli C; Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.; IRCCS C. Mondino Foundation, Pavia, Italy., Vernieri F; Unit of Headache and Neurosonology, Fondazione Policlinico Campus Bio-Medico, Rome, Italy.; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy., Lantéri-Minet M; Pain Department, UR2CA, FHU InovPain, Côte Azur University and Centre Hospitalier Universitaire de Nice, Nice, France.; INSERM U1107 Migraine and Trigeminal Pain, Auvergne University, Clermont-Ferrand, France., Terwindt GM; Department of Neurology, Leiden University Medical Centre, Leiden, Netherlands., Blumenfeld A; The Los Angeles Headache Center, Los Angeles, CA, USA., Tepper SJ; The New England Institute for Neurology and Headache, Stamford, CT, USA., Josiassen MK; H. Lundbeck A/S, Copenhagen, Denmark., Jansson G; H. Lundbeck A/S, Copenhagen, Denmark., Ettrup A; H. Lundbeck A/S, Copenhagen, Denmark., Mittoux A; H. Lundbeck A/S, Copenhagen, Denmark., Lipton RB; Department of Neurology and Montefiore Headache Center, Albert Einstein College of Medicine, New York, NY, USA.
Source: The journal of headache and pain [J Headache Pain] 2026 Jun 13; Vol. 27 (1). Date of Electronic Publication: 2026 Jun 13.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase IV
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100940562 Publication Model: Electronic Cited Medium: Internet ISSN: 1129-2377 (Electronic) Linking ISSN: 11292369 NLM ISO Abbreviation: J Headache Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1129-2377
DOI:10.1186/s10194-026-02423-x