Acute pretrauma ethanol exacerbates PTSD-like phenotype in rats and is reversed by early intranasal ketamine.

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Title: Acute pretrauma ethanol exacerbates PTSD-like phenotype in rats and is reversed by early intranasal ketamine.
Authors: Yogev BE; Department of Psychology, Ben-Gurion University of the Negev, Beer-Sheva, Israel.; Anxiety and Stress Research Unit, Ministry of Health, Be'erot Mental Health Center, Beer-Sheva, Israel., Levi G; Department of Psychology, Ben-Gurion University of the Negev, Beer-Sheva, Israel.; Anxiety and Stress Research Unit, Ministry of Health, Be'erot Mental Health Center, Beer-Sheva, Israel., Efroni N; Anxiety and Stress Research Unit, Ministry of Health, Be'erot Mental Health Center, Beer-Sheva, Israel., Sintov AC; Department of Biomedical Engineering, Faculty of Engineering Sciences, Ben- Gurion University of the Negev, Beer-Sheva, Israel., Todder D; Anxiety and Stress Research Unit, Ministry of Health, Be'erot Mental Health Center, Beer-Sheva, Israel.; Faculty of Health Sciences, Ben-Gurion University of the Negev, P. O. Box 4600, 84170, Beer-Sheva, Israel., Zohar J; Post-Trauma Center, Sheba Medical Center, Tel Aviv University, Tel Aviv, 52621, Israel., Cohen H; Department of Psychology, Ben-Gurion University of the Negev, Beer-Sheva, Israel. hagitc@bgu.ac.il.; Anxiety and Stress Research Unit, Ministry of Health, Be'erot Mental Health Center, Beer-Sheva, Israel. hagitc@bgu.ac.il.; Faculty of Health Sciences, Ben-Gurion University of the Negev, P. O. Box 4600, 84170, Beer-Sheva, Israel. hagitc@bgu.ac.il.
Source: Scientific reports [Sci Rep] 2026 Jun 14. Date of Electronic Publication: 2026 Jun 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Acute pretrauma ethanol exacerbates PTSD-like phenotype in rats and is reversed by early intranasal ketamine.
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  Data: <searchLink fieldCode="AU" term="%22Yogev+BE%22">Yogev BE</searchLink>; Department of Psychology, Ben-Gurion University of the Negev, Beer-Sheva, Israel.; Anxiety and Stress Research Unit, Ministry of Health, Be'erot Mental Health Center, Beer-Sheva, Israel.<br /><searchLink fieldCode="AU" term="%22Levi+G%22">Levi G</searchLink>; Department of Psychology, Ben-Gurion University of the Negev, Beer-Sheva, Israel.; Anxiety and Stress Research Unit, Ministry of Health, Be'erot Mental Health Center, Beer-Sheva, Israel.<br /><searchLink fieldCode="AU" term="%22Efroni+N%22">Efroni N</searchLink>; Anxiety and Stress Research Unit, Ministry of Health, Be'erot Mental Health Center, Beer-Sheva, Israel.<br /><searchLink fieldCode="AU" term="%22Sintov+AC%22">Sintov AC</searchLink>; Department of Biomedical Engineering, Faculty of Engineering Sciences, Ben- Gurion University of the Negev, Beer-Sheva, Israel.<br /><searchLink fieldCode="AU" term="%22Todder+D%22">Todder D</searchLink>; Anxiety and Stress Research Unit, Ministry of Health, Be'erot Mental Health Center, Beer-Sheva, Israel.; Faculty of Health Sciences, Ben-Gurion University of the Negev, P. O. Box 4600, 84170, Beer-Sheva, Israel.<br /><searchLink fieldCode="AU" term="%22Zohar+J%22">Zohar J</searchLink>; Post-Trauma Center, Sheba Medical Center, Tel Aviv University, Tel Aviv, 52621, Israel.<br /><searchLink fieldCode="AU" term="%22Cohen+H%22">Cohen H</searchLink>; Department of Psychology, Ben-Gurion University of the Negev, Beer-Sheva, Israel. hagitc@bgu.ac.il.; Anxiety and Stress Research Unit, Ministry of Health, Be'erot Mental Health Center, Beer-Sheva, Israel. hagitc@bgu.ac.il.; Faculty of Health Sciences, Ben-Gurion University of the Negev, P. O. Box 4600, 84170, Beer-Sheva, Israel. hagitc@bgu.ac.il.
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        Value: 10.1038/s41598-026-56757-2
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        Text: English
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      – TitleFull: Acute pretrauma ethanol exacerbates PTSD-like phenotype in rats and is reversed by early intranasal ketamine.
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              Text: 2026 Jun 14
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