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Timing of device-aided therapy initiation in Parkinson's disease: reference estimates for healthcare planning and biological heterogeneity.

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Title: Timing of device-aided therapy initiation in Parkinson's disease: reference estimates for healthcare planning and biological heterogeneity.
Authors: Ledingham D; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom.; Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle Upon Tyne, United Kingdom.; Translational and Clinical Research Institute, The Medical School, Newcastle University, Newcastle Upon Tyne, United Kingdom.; NIHR Newcastle Biomedical Research Centre (BRC), Newcastle upon Tyne, UK., Stewart CB; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom.; Translational and Clinical Research Institute, The Medical School, Newcastle University, Newcastle Upon Tyne, United Kingdom.; NIHR Newcastle Biomedical Research Centre (BRC), Newcastle upon Tyne, UK., Sathyanarayana S; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom.; Translational and Clinical Research Institute, The Medical School, Newcastle University, Newcastle Upon Tyne, United Kingdom.; NIHR Newcastle Biomedical Research Centre (BRC), Newcastle upon Tyne, UK., Foster V; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom., Iredale R; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom., Galley D; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom., Baker MR; Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle Upon Tyne, United Kingdom.; Translational and Clinical Research Institute, The Medical School, Newcastle University, Newcastle Upon Tyne, United Kingdom.; NIHR Newcastle Biomedical Research Centre (BRC), Newcastle upon Tyne, UK., Pavese N; Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom.; Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle Upon Tyne, United Kingdom.; Translational and Clinical Research Institute, The Medical School, Newcastle University, Newcastle Upon Tyne, United Kingdom.; Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Aarhus, Denmark.; NIHR Newcastle Biomedical Research Centre (BRC), Newcastle upon Tyne, UK.
Source: Clinical parkinsonism & related disorders [Clin Park Relat Disord] 2026 Jun 04; Vol. 14, pp. 100458. Date of Electronic Publication: 2026 Jun 04 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101761473 Publication Model: eCollection Cited Medium: Internet ISSN: 2590-1125 (Electronic) Linking ISSN: 25901125 NLM ISO Abbreviation: Clin Park Relat Disord Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2590-1125
DOI:10.1016/j.prdoa.2026.100458