Liuwei dihuang decoction attenuates intervertebral disc degeneration by inhibiting TRPA1-Mediated ferroptosis in endplate chondrocytes.

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Title: Liuwei dihuang decoction attenuates intervertebral disc degeneration by inhibiting TRPA1-Mediated ferroptosis in endplate chondrocytes.
Authors: Xu R; Department of spine surgery, Affiliated hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China., Yang Y; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Xu P; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Qin K; Department of Operations Management, Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China., Li O; State Key Laboratory of Food Science and Resources, China-Canada Joint Lab of Food Science and Technology (Nanchang), Nanchang University, Nanchang, Jiangxi, China.; Jiangxi Institute of Quality and Standardization, Nanchang, Jiangxi, China., Wu T; Department of spine surgery, Affiliated hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China., Pan Y; Department of Pharmaceutical Engineering, School of Biomedical Sciences, Daegu Catholic University, Gyeongsan-si, South Korea., Sheng C; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Xie Z; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Wu M; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Wang J; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Wang W; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Ma T; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Jin Z; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Jiang D; Department of Pharmaceutical Engineering, School of Biomedical Sciences, Daegu Catholic University, Gyeongsan-si, South Korea., Xia H; Department of spine surgery, Affiliated hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.; Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China., Li Y; Department of spine surgery, Affiliated hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.
Source: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2026 May 29; Vol. 14, pp. 1759798. Date of Electronic Publication: 2026 May 29 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2296-634X
DOI:10.3389/fcell.2026.1759798