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Liuwei dihuang decoction attenuates intervertebral disc degeneration by inhibiting TRPA1-Mediated ferroptosis in endplate chondrocytes.

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Title: Liuwei dihuang decoction attenuates intervertebral disc degeneration by inhibiting TRPA1-Mediated ferroptosis in endplate chondrocytes.
Authors: Xu R; Department of spine surgery, Affiliated hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China., Yang Y; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Xu P; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Qin K; Department of Operations Management, Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China., Li O; State Key Laboratory of Food Science and Resources, China-Canada Joint Lab of Food Science and Technology (Nanchang), Nanchang University, Nanchang, Jiangxi, China.; Jiangxi Institute of Quality and Standardization, Nanchang, Jiangxi, China., Wu T; Department of spine surgery, Affiliated hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China., Pan Y; Department of Pharmaceutical Engineering, School of Biomedical Sciences, Daegu Catholic University, Gyeongsan-si, South Korea., Sheng C; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Xie Z; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Wu M; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Wang J; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Wang W; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Ma T; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Jin Z; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China., Jiang D; Department of Pharmaceutical Engineering, School of Biomedical Sciences, Daegu Catholic University, Gyeongsan-si, South Korea., Xia H; Department of spine surgery, Affiliated hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.; Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China., Li Y; Department of spine surgery, Affiliated hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.
Source: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2026 May 29; Vol. 14, pp. 1759798. Date of Electronic Publication: 2026 May 29 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Liuwei dihuang decoction attenuates intervertebral disc degeneration by inhibiting TRPA1-Mediated ferroptosis in endplate chondrocytes.
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  Data: <searchLink fieldCode="AU" term="%22Xu+R%22">Xu R</searchLink>; Department of spine surgery, Affiliated hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Xu+P%22">Xu P</searchLink>; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Qin+K%22">Qin K</searchLink>; Department of Operations Management, Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.<br /><searchLink fieldCode="AU" term="%22Li+O%22">Li O</searchLink>; State Key Laboratory of Food Science and Resources, China-Canada Joint Lab of Food Science and Technology (Nanchang), Nanchang University, Nanchang, Jiangxi, China.; Jiangxi Institute of Quality and Standardization, Nanchang, Jiangxi, China.<br /><searchLink fieldCode="AU" term="%22Wu+T%22">Wu T</searchLink>; Department of spine surgery, Affiliated hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.<br /><searchLink fieldCode="AU" term="%22Pan+Y%22">Pan Y</searchLink>; Department of Pharmaceutical Engineering, School of Biomedical Sciences, Daegu Catholic University, Gyeongsan-si, South Korea.<br /><searchLink fieldCode="AU" term="%22Sheng+C%22">Sheng C</searchLink>; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Xie+Z%22">Xie Z</searchLink>; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Wu+M%22">Wu M</searchLink>; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Wang+W%22">Wang W</searchLink>; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Ma+T%22">Ma T</searchLink>; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Jin+Z%22">Jin Z</searchLink>; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Jiang+D%22">Jiang D</searchLink>; Department of Pharmaceutical Engineering, School of Biomedical Sciences, Daegu Catholic University, Gyeongsan-si, South Korea.<br /><searchLink fieldCode="AU" term="%22Xia+H%22">Xia H</searchLink>; Department of spine surgery, Affiliated hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.; Zhejiang Provincial Chinese Medicine Hospital (First affiliated hospital of Zhejiang Chinese Medical University), Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.; Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of spine surgery, Affiliated hospital of Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.
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  Data: <searchLink fieldCode="JN" term="%22101630250%22">Frontiers in cell and developmental biology</searchLink> [Front Cell Dev Biol] 2026 May 29; Vol. 14, pp. 1759798. <i>Date of Electronic Publication: </i>2026 May 29 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media+S%2EA%22">Frontiers Media S.A </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101630250 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2296-634X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222296634X%22">2296634X </searchLink><i>NLM ISO Abbreviation: </i>Front Cell Dev Biol <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3389/fcell.2026.1759798
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      – Code: eng
        Text: English
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      – TitleFull: Liuwei dihuang decoction attenuates intervertebral disc degeneration by inhibiting TRPA1-Mediated ferroptosis in endplate chondrocytes.
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              Text: 2026 May 29
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