Enterococcus faecalis autolysin EpaU binds the enterococcal polysaccharide antigen via its teichoic acid-like repeats and modulates c-di-AMP signaling.

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Title: Enterococcus faecalis autolysin EpaU binds the enterococcal polysaccharide antigen via its teichoic acid-like repeats and modulates c-di-AMP signaling.
Authors: Chaton CT; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, USA., Murner NR; Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky, Lexington, Kentucky, USA., Zamakhaeva S; Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky, Lexington, Kentucky, USA., Rush JS; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, USA., Kenner CW; Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky, Lexington, Kentucky, USA., Yarawsky AE; BioAnalysis LLC, Philadelphia, Pennsylvania, USA., Huang L; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA., Azadi P; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA., Herr AB; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., Korotkova N; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, USA.; Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky, Lexington, Kentucky, USA., Korotkov KV; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, USA.
Source: MBio [mBio] 2026 Jul 08; Vol. 17 (7), pp. e0098826. Date of Electronic Publication: 2026 Jun 15.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2150-7511
DOI:10.1128/mbio.00988-26