A myeloid immunosuppressive phenotype defines primary refractoriness to atezolizumab plus bevacizumab in hepatocellular carcinoma.
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| Title: | A myeloid immunosuppressive phenotype defines primary refractoriness to atezolizumab plus bevacizumab in hepatocellular carcinoma. |
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| Authors: | Lombardi P; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Phase 1 Unit, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy., Ramon-Gil E; The Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne, U.K., Raja RQ; The Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne, U.K., Brunetti L; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK., Manfredi GF; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy., Zhou Z; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK., Merces G; Image Analysis Unit, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Cappuyns S; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Digestive Oncology, Department of Gastroenterology and Hepatology, UZ/KU Leuven, Belgium., Fulgenzi CAM; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK., D'Alessio A; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK., Torkpour A; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK., Celsa C; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Section of Gastroenterology & Hepatology, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, PROMISE, University of Palermo, Palermo, Italy., Stefanini B; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Department of Medical and Surgical Sciences, University of Bologna, Italy., Yang H; Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea., Crowley F; Department of Medicine, Division of Hematology/Oncology, Tisch Cancer Institute, Mount Sinai Hospital, New York, NY, USA., Marron TU; Department of Medicine, Division of Hematology/Oncology, Tisch Cancer Institute, Mount Sinai Hospital, New York, NY, USA., Saeed A; Department of Medicine, Division of Hematology & Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Pinter M; Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria., Scheiner B; Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria., Huang YH; Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Lee PC; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan., Nishida N; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka, Japan., Po-Ting Lin R; Department of Gastroenterology and Hepatology, Chang Gung Medical Foundation, Linkou Chang Gung Memorial Hospital, Taiwan NO 5, Fu-Hsing Street, Kuei Shan, Taoyuan 333, Taiwan., Dalbeni A; University of Verona, Department of Medicine General Medicine C Unit & Liver Unit., Vivaldi C; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy., Masi G; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy., Rohlen N; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, University of Freiburg, Freiburg, Germany., von Felden J; Department of Oncology, Hematology and Bone Marrow Transplantation with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Kaseb A; Gastrointestinal Medical Oncology Department, University of Texas MD Anderson Cancer Center, Houston, TX., Galle PR; University Medical Center Mainz, I. Dept. of Internal Medicine, Mainz, Germany., Kudo M; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka, Japan., Hsu WF; Department of Internal Medicine, Center for Digestive Medicine, China Medical University Hospital, Taichung, Taiwan., Rimassa L; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Milan, Italy; Hepatopancreatobiliary Oncology , Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Via A. Manzoni 56, 20089 Rozzano, Milan, Italy., Parisi A; Department of Oncology, Università Politecnica delle Marche, Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy., Kelley RK; Department of Medicine (Hematology/Oncology), UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA., Toyoda H; Department of Gastroenterology and Hepatology, Ogaki Municipal Hospital, Ogaki, Japan., Pirisi M; Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy., Jabar F; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Department of Clinical Pathology, University Hospital of North Norway, Tromsø, Norway., Rakaee M; Department of Clinical Pathology, University Hospital of North Norway, Tromsø, Norway; Department of Cancer Genetics, Oslo University Hospital, Oslo, Norway; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Department of Medical Biology, UiT The Arctic University of Norway, Tromsø, Norway., Cabibbo G; Section of Gastroenterology & Hepatology, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, PROMISE, University of Palermo, Palermo, Italy; Department of Surgical, Oncological and Oral Sciences (Di.Chir.On.S.), University of Palermo, Italy., Cammà C; Section of Gastroenterology & Hepatology, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, PROMISE, University of Palermo, Palermo, Italy., Piscaglia F; Department of Medical and Surgical Sciences, University of Bologna, Italy; Division of Internal Medicine, Hepatobiliary and Immunoallergic Diseases, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy., Hwang S; Department of Pathology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Republic of Korea., Shin DJ; Department of Biomedical Science, College of Life Science, CHA University School of Medicine, Seongnam, Republic of Korea., Li M; Division of Gastroenterology and Hepatology, University of California, San Francisco, California, USA., Dekervel J; Digestive Oncology, Department of Gastroenterology and Hepatology, UZ/KU Leuven, Belgium., Guerra N; Department of Life Sciences, Imperial College London, South Kensington Campus, Exhibition Road, London, SW7 2AZ, UK., Meyer T; Research Department of Oncology, UCL Cancer Institute, University College London, Royal Free Hospital, London, UK., Reeves HL; The Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne, U.K; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK; NIHR, Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, Tyne and Wear, UK., Bengsch B; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, University of Freiburg, Freiburg, Germany., Daniele G; Phase 1 Unit, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy., Mann DA; The Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne, U.K., Chon HJ; Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea. Electronic address: minidoctor@cha.ac.kr., Leslie J; The Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne, U.K; NIHR, Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, Tyne and Wear, UK. Electronic address: Jack.Leslie@newcastle.ac.uk., Pinato DJ; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy. Electronic address: david.pinato@imperial.ac.uk. |
| Source: | Journal of hepatology [J Hepatol] 2026 Jun 15. Date of Electronic Publication: 2026 Jun 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42297215 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A myeloid immunosuppressive phenotype defines primary refractoriness to atezolizumab plus bevacizumab in hepatocellular carcinoma. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Lombardi+P%22">Lombardi P</searchLink>; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Phase 1 Unit, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ramon-Gil+E%22">Ramon-Gil E</searchLink>; The Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne, U.K.<br /><searchLink fieldCode="AU" term="%22Raja+RQ%22">Raja RQ</searchLink>; The Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne, U.K.<br /><searchLink fieldCode="AU" term="%22Brunetti+L%22">Brunetti L</searchLink>; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK.<br /><searchLink fieldCode="AU" term="%22Manfredi+GF%22">Manfredi GF</searchLink>; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy.<br /><searchLink fieldCode="AU" term="%22Zhou+Z%22">Zhou Z</searchLink>; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK.<br /><searchLink fieldCode="AU" term="%22Merces+G%22">Merces G</searchLink>; Image Analysis Unit, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Cappuyns+S%22">Cappuyns S</searchLink>; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Digestive Oncology, Department of Gastroenterology and Hepatology, UZ/KU Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Fulgenzi+CAM%22">Fulgenzi CAM</searchLink>; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK.<br /><searchLink fieldCode="AU" term="%22D'Alessio+A%22">D'Alessio A</searchLink>; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK.<br /><searchLink fieldCode="AU" term="%22Torkpour+A%22">Torkpour A</searchLink>; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK.<br /><searchLink fieldCode="AU" term="%22Celsa+C%22">Celsa C</searchLink>; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Section of Gastroenterology & Hepatology, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, PROMISE, University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Stefanini+B%22">Stefanini B</searchLink>; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Department of Medical and Surgical Sciences, University of Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Crowley+F%22">Crowley F</searchLink>; Department of Medicine, Division of Hematology/Oncology, Tisch Cancer Institute, Mount Sinai Hospital, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Marron+TU%22">Marron TU</searchLink>; Department of Medicine, Division of Hematology/Oncology, Tisch Cancer Institute, Mount Sinai Hospital, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Saeed+A%22">Saeed A</searchLink>; Department of Medicine, Division of Hematology & Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Pinter+M%22">Pinter M</searchLink>; Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Scheiner+B%22">Scheiner B</searchLink>; Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Huang+YH%22">Huang YH</searchLink>; Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+PC%22">Lee PC</searchLink>; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Nishida+N%22">Nishida N</searchLink>; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Po-Ting+Lin+R%22">Po-Ting Lin R</searchLink>; Department of Gastroenterology and Hepatology, Chang Gung Medical Foundation, Linkou Chang Gung Memorial Hospital, Taiwan NO 5, Fu-Hsing Street, Kuei Shan, Taoyuan 333, Taiwan.<br /><searchLink fieldCode="AU" term="%22Dalbeni+A%22">Dalbeni A</searchLink>; University of Verona, Department of Medicine General Medicine C Unit & Liver Unit.<br /><searchLink fieldCode="AU" term="%22Vivaldi+C%22">Vivaldi C</searchLink>; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Masi+G%22">Masi G</searchLink>; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Rohlen+N%22">Rohlen N</searchLink>; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22von+Felden+J%22">von Felden J</searchLink>; Department of Oncology, Hematology and Bone Marrow Transplantation with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kaseb+A%22">Kaseb A</searchLink>; Gastrointestinal Medical Oncology Department, University of Texas MD Anderson Cancer Center, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Galle+PR%22">Galle PR</searchLink>; University Medical Center Mainz, I. Dept. of Internal Medicine, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Kudo+M%22">Kudo M</searchLink>; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Hsu+WF%22">Hsu WF</searchLink>; Department of Internal Medicine, Center for Digestive Medicine, China Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Rimassa+L%22">Rimassa L</searchLink>; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Milan, Italy; Hepatopancreatobiliary Oncology , Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Via A. Manzoni 56, 20089 Rozzano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Parisi+A%22">Parisi A</searchLink>; Department of Oncology, Università Politecnica delle Marche, Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Kelley+RK%22">Kelley RK</searchLink>; Department of Medicine (Hematology/Oncology), UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Toyoda+H%22">Toyoda H</searchLink>; Department of Gastroenterology and Hepatology, Ogaki Municipal Hospital, Ogaki, Japan.<br /><searchLink fieldCode="AU" term="%22Pirisi+M%22">Pirisi M</searchLink>; Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy.<br /><searchLink fieldCode="AU" term="%22Jabar+F%22">Jabar F</searchLink>; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Department of Clinical Pathology, University Hospital of North Norway, Tromsø, Norway.<br /><searchLink fieldCode="AU" term="%22Rakaee+M%22">Rakaee M</searchLink>; Department of Clinical Pathology, University Hospital of North Norway, Tromsø, Norway; Department of Cancer Genetics, Oslo University Hospital, Oslo, Norway; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Department of Medical Biology, UiT The Arctic University of Norway, Tromsø, Norway.<br /><searchLink fieldCode="AU" term="%22Cabibbo+G%22">Cabibbo G</searchLink>; Section of Gastroenterology & Hepatology, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, PROMISE, University of Palermo, Palermo, Italy; Department of Surgical, Oncological and Oral Sciences (Di.Chir.On.S.), University of Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Cammà+C%22">Cammà C</searchLink>; Section of Gastroenterology & Hepatology, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, PROMISE, University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Piscaglia+F%22">Piscaglia F</searchLink>; Department of Medical and Surgical Sciences, University of Bologna, Italy; Division of Internal Medicine, Hepatobiliary and Immunoallergic Diseases, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Hwang+S%22">Hwang S</searchLink>; Department of Pathology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+DJ%22">Shin DJ</searchLink>; Department of Biomedical Science, College of Life Science, CHA University School of Medicine, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Division of Gastroenterology and Hepatology, University of California, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Dekervel+J%22">Dekervel J</searchLink>; Digestive Oncology, Department of Gastroenterology and Hepatology, UZ/KU Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Guerra+N%22">Guerra N</searchLink>; Department of Life Sciences, Imperial College London, South Kensington Campus, Exhibition Road, London, SW7 2AZ, UK.<br /><searchLink fieldCode="AU" term="%22Meyer+T%22">Meyer T</searchLink>; Research Department of Oncology, UCL Cancer Institute, University College London, Royal Free Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Reeves+HL%22">Reeves HL</searchLink>; The Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne, U.K; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK; NIHR, Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, Tyne and Wear, UK.<br /><searchLink fieldCode="AU" term="%22Bengsch+B%22">Bengsch B</searchLink>; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Daniele+G%22">Daniele G</searchLink>; Phase 1 Unit, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mann+DA%22">Mann DA</searchLink>; The Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne, U.K.<br /><searchLink fieldCode="AU" term="%22Chon+HJ%22">Chon HJ</searchLink>; Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea. Electronic address: minidoctor@cha.ac.kr.<br /><searchLink fieldCode="AU" term="%22Leslie+J%22">Leslie J</searchLink>; The Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne, U.K; NIHR, Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, Tyne and Wear, UK. Electronic address: Jack.Leslie@newcastle.ac.uk.<br /><searchLink fieldCode="AU" term="%22Pinato+DJ%22">Pinato DJ</searchLink>; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK; Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy. Electronic address: david.pinato@imperial.ac.uk. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228503886%22">Journal of hepatology</searchLink> [J Hepatol] 2026 Jun 15. <i>Date of Electronic Publication: </i>2026 Jun 15. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8503886 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1600-0641 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201688278%22">01688278 </searchLink><i>NLM ISO Abbreviation: </i>J Hepatol <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jhep.2026.05.018 Languages: – Code: eng Text: English Titles: – TitleFull: A myeloid immunosuppressive phenotype defines primary refractoriness to atezolizumab plus bevacizumab in hepatocellular carcinoma. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lombardi P – PersonEntity: Name: NameFull: Ramon-Gil E – PersonEntity: Name: NameFull: Raja RQ – PersonEntity: Name: NameFull: Brunetti L – PersonEntity: Name: NameFull: Manfredi GF – PersonEntity: Name: NameFull: Zhou Z – PersonEntity: Name: NameFull: Merces G – PersonEntity: Name: NameFull: Cappuyns S – PersonEntity: Name: NameFull: Fulgenzi CAM – PersonEntity: Name: NameFull: D'Alessio A – PersonEntity: Name: NameFull: Torkpour A – PersonEntity: Name: NameFull: Celsa C – PersonEntity: Name: NameFull: Stefanini B – PersonEntity: Name: NameFull: Yang H – PersonEntity: Name: NameFull: Crowley F – PersonEntity: Name: NameFull: Marron TU – PersonEntity: Name: NameFull: Saeed A – PersonEntity: Name: NameFull: Pinter M – PersonEntity: Name: NameFull: Scheiner B – PersonEntity: Name: NameFull: Huang YH – PersonEntity: Name: NameFull: Lee PC – PersonEntity: Name: NameFull: Nishida N – PersonEntity: Name: NameFull: Po-Ting Lin R – PersonEntity: Name: NameFull: Dalbeni A – PersonEntity: Name: NameFull: Vivaldi C – PersonEntity: Name: NameFull: Masi G – PersonEntity: Name: NameFull: Rohlen N – PersonEntity: Name: NameFull: von Felden J – PersonEntity: Name: NameFull: Kaseb A – PersonEntity: Name: NameFull: Galle PR – PersonEntity: Name: NameFull: Kudo M – PersonEntity: Name: NameFull: Hsu WF – PersonEntity: Name: NameFull: Rimassa L – PersonEntity: Name: NameFull: Parisi A – PersonEntity: Name: NameFull: Kelley RK – PersonEntity: Name: NameFull: Toyoda H – PersonEntity: Name: NameFull: Pirisi M – PersonEntity: Name: NameFull: Jabar F – PersonEntity: Name: NameFull: Rakaee M – PersonEntity: Name: NameFull: Cabibbo G – PersonEntity: Name: NameFull: Cammà C – PersonEntity: Name: NameFull: Piscaglia F – PersonEntity: Name: NameFull: Hwang S – PersonEntity: Name: NameFull: Shin DJ – PersonEntity: Name: NameFull: Li M – PersonEntity: Name: NameFull: Dekervel J – PersonEntity: Name: NameFull: Guerra N – PersonEntity: Name: NameFull: Meyer T – PersonEntity: Name: NameFull: Reeves HL – PersonEntity: Name: NameFull: Bengsch B – PersonEntity: Name: NameFull: Daniele G – PersonEntity: Name: NameFull: Mann DA – PersonEntity: Name: NameFull: Chon HJ – PersonEntity: Name: NameFull: Leslie J – PersonEntity: Name: NameFull: Pinato DJ IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 06 Text: 2026 Jun 15 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1600-0641 Titles: – TitleFull: Journal of hepatology Type: main |
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