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Targeting the senescence‒autophagy axis via p16INK4a inhibition alleviates pulmonary fibrosis.

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Title: Targeting the senescence‒autophagy axis via p16INK4a inhibition alleviates pulmonary fibrosis.
Authors: Yoo YJ; Graduate School of Pharmaceutical Sciences and College of Pharmacy, Seoul, Republic of Korea., Zhang M; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Jin SH; Innovative BioPharmChem Convergence Education and Research Program, Ewha Womans University, Seoul, Republic of Korea., Lee YR; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Jin H; Graduate School of Pharmaceutical Sciences and College of Pharmacy, Seoul, Republic of Korea., Doan TP; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Kim S; Graduate School of Pharmaceutical Sciences and College of Pharmacy, Seoul, Republic of Korea., Choi S; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Park EJ; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Sookmyung Women's University, Seoul, Republic of Korea., Na S; Innovative BioPharmChem Convergence Education and Research Program, Ewha Womans University, Seoul, Republic of Korea., Lee Y; Innovative BioPharmChem Convergence Education and Research Program, Ewha Womans University, Seoul, Republic of Korea., Sun J; Innovative BioPharmChem Convergence Education and Research Program, Ewha Womans University, Seoul, Republic of Korea., Cho J; Department of Radiation Oncology, Yonsei University Health System, Seoul, Republic of Korea., Cho NC; Drug Information Platform Center, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea., Park SY; Graduate School of Pharmaceutical Sciences and College of Pharmacy, Seoul, Republic of Korea. syeonp@ewha.ac.kr., Oh WK; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea. wkoh1@snu.ac.kr., Lee YS; Graduate School of Pharmaceutical Sciences and College of Pharmacy, Seoul, Republic of Korea. yslee0425@ewha.ac.kr.; Innovative BioPharmChem Convergence Education and Research Program, Ewha Womans University, Seoul, Republic of Korea. yslee0425@ewha.ac.kr.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Jun 15; Vol. 11 (1). Date of Electronic Publication: 2026 Jun 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting the senescence‒autophagy axis via p16<superscript>INK4a</superscript> inhibition alleviates pulmonary fibrosis.
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  Data: <searchLink fieldCode="AU" term="%22Yoo+YJ%22">Yoo YJ</searchLink>; Graduate School of Pharmaceutical Sciences and College of Pharmacy, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Zhang+M%22">Zhang M</searchLink>; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jin+SH%22">Jin SH</searchLink>; Innovative BioPharmChem Convergence Education and Research Program, Ewha Womans University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+YR%22">Lee YR</searchLink>; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jin+H%22">Jin H</searchLink>; Graduate School of Pharmaceutical Sciences and College of Pharmacy, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Doan+TP%22">Doan TP</searchLink>; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Graduate School of Pharmaceutical Sciences and College of Pharmacy, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+S%22">Choi S</searchLink>; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+EJ%22">Park EJ</searchLink>; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Sookmyung Women's University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Na+S%22">Na S</searchLink>; Innovative BioPharmChem Convergence Education and Research Program, Ewha Womans University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+Y%22">Lee Y</searchLink>; Innovative BioPharmChem Convergence Education and Research Program, Ewha Womans University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sun+J%22">Sun J</searchLink>; Innovative BioPharmChem Convergence Education and Research Program, Ewha Womans University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+J%22">Cho J</searchLink>; Department of Radiation Oncology, Yonsei University Health System, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+NC%22">Cho NC</searchLink>; Drug Information Platform Center, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+SY%22">Park SY</searchLink>; Graduate School of Pharmaceutical Sciences and College of Pharmacy, Seoul, Republic of Korea. syeonp@ewha.ac.kr.<br /><searchLink fieldCode="AU" term="%22Oh+WK%22">Oh WK</searchLink>; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea. wkoh1@snu.ac.kr.<br /><searchLink fieldCode="AU" term="%22Lee+YS%22">Lee YS</searchLink>; Graduate School of Pharmaceutical Sciences and College of Pharmacy, Seoul, Republic of Korea. yslee0425@ewha.ac.kr.; Innovative BioPharmChem Convergence Education and Research Program, Ewha Womans University, Seoul, Republic of Korea. yslee0425@ewha.ac.kr.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101676423 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-3635 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220593635%22">20593635 </searchLink><i>NLM ISO Abbreviation: </i>Signal Transduct Target Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41392-026-02730-4
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              Text: 2026 Jun 15
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