CYP46A1-Targeted Treatment Alleviates Long-Term White Matter Injury Following Traumatic Brain Injury by Promoting Cholesterol Metabolic Clearance and Remyelination.
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| Title: | CYP46A1-Targeted Treatment Alleviates Long-Term White Matter Injury Following Traumatic Brain Injury by Promoting Cholesterol Metabolic Clearance and Remyelination. |
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| Authors: | Li L; Department of Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Shi Y; Department of Neuro-Oncology, Chongqing University Cancer Hospital, Chongqing, China., Luo Q; Department of Ultrasound, Chonggang General Hospital, Chongqing University of Posts and Telecommunications, Chongqing, China., Guo P; Department of Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Jin T; Department of Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Ru X; Department of Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Jiang Z; Department of Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Niu Y; Department of Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Li W; Department of Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Chen Y; Department of Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Chen Z; Department of Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China. |
| Source: | CNS neuroscience & therapeutics [CNS Neurosci Ther] 2026 Jun; Vol. 32 (6), pp. e70984. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949 (Electronic) Linking ISSN: 17555930 NLM ISO Abbreviation: CNS Neurosci Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1755-5949 |
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| DOI: | 10.1002/cns.70984 |
