Microdomain-resolved potassium channel gating as a controllable process: patient-specific excitability landscapes, attractor stability, and closed-loop therapeutic optimization.

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Title: Microdomain-resolved potassium channel gating as a controllable process: patient-specific excitability landscapes, attractor stability, and closed-loop therapeutic optimization.
Authors: Condorelli GA; Research Centre in the Medical-Pharmaceutical Field, Department of Pharmaceutical Science, Faculty of Medicine and Pharmacy, 'Dunarea de Jos' University of Galati, Galati, Romania.; Department of Biomedical and Biotechnological Sciences, Section of Pharmacology, University of Catania, Catania, Italy., Genova R; Faculty of Medicine and Pharmacy, 'Dunarea de Jos' University of Galati, Galati, Romania., D'Urso O; Department of Biomedical and Biotechnological Sciences, Section of Pharmacology, University of Catania, Catania, Italy., Dragostin OM; Research Centre in the Medical-Pharmaceutical Field, Department of Pharmaceutical Science, Faculty of Medicine and Pharmacy, 'Dunarea de Jos' University of Galati, Galati, Romania.
Source: Expert opinion on pharmacotherapy [Expert Opin Pharmacother] 2026 Jul; Vol. 27 (10), pp. 875-898. Date of Electronic Publication: 2026 Jun 19.
Publication Type: Journal Article; Review
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 100897346 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7666 (Electronic) Linking ISSN: 14656566 NLM ISO Abbreviation: Expert Opin Pharmacother Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1744-7666
DOI:10.1080/14656566.2026.2689546