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Design, synthesis, and evaluation of trisubstituted bicyclo[2.2.2]oct-2-enes as non-classical isosteres of trisubstituted benzenes.

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Bibliographic Details
Title: Design, synthesis, and evaluation of trisubstituted bicyclo[2.2.2]oct-2-enes as non-classical isosteres of trisubstituted benzenes.
Authors: Hsu CW; Department of Chemistry, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan. woojinyoo@ntu.edu.tw., Liu WQ; Department of Chemistry, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan. woojinyoo@ntu.edu.tw., Shih FJ; Department of Chemistry, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan. woojinyoo@ntu.edu.tw., Jheng YJ; Department of Chemistry, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan. woojinyoo@ntu.edu.tw., Chou CH; Department of Chemistry, National Taiwan Normal University, No. 162, Sec. 1, Heping E. Road, Taipei 11677, Taiwan. sfchen@ntnu.edu.tw., Wang YM; Department of Chemistry, National Taiwan Normal University, No. 162, Sec. 1, Heping E. Road, Taipei 11677, Taiwan. sfchen@ntnu.edu.tw., Chen SF; Department of Chemistry, National Taiwan Normal University, No. 162, Sec. 1, Heping E. Road, Taipei 11677, Taiwan. sfchen@ntnu.edu.tw., Chu J; Department of Chemistry, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan. woojinyoo@ntu.edu.tw.; Center for Emerging Materials and Advanced Devices, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan., Yoo WJ; Department of Chemistry, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan. woojinyoo@ntu.edu.tw.; Center for Emerging Materials and Advanced Devices, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan.
Source: Organic & biomolecular chemistry [Org Biomol Chem] 2026 Jul 08; Vol. 24 (26), pp. 5488-5493. Date of Electronic Publication: 2026 Jul 08.
Publication Type: Journal Article
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-0539 (Electronic) Linking ISSN: 14770520 NLM ISO Abbreviation: Org Biomol Chem Subsets: MEDLINE; PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1477-0539
DOI:10.1039/d6ob00798h