Detailed pharmacokinetic features of a novel bis-boron 18F-trifluoroborate acid in healthy volunteers: comparable and additional values of total-body PET-imaging-derived analysis.

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Title: Detailed pharmacokinetic features of a novel bis-boron 18F-trifluoroborate acid in healthy volunteers: comparable and additional values of total-body PET-imaging-derived analysis.
Authors: Liu G; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Shanghai Institute of Medical Imaging, Shanghai, 200032, China.; Institute of Nuclear Medicine, Fudan University, Shanghai, 200032, China., Xu H; Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China., Lv J; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Shanghai Institute of Medical Imaging, Shanghai, 200032, China.; Institute of Nuclear Medicine, Fudan University, Shanghai, 200032, China., Xie Y; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Shanghai Institute of Medical Imaging, Shanghai, 200032, China.; Institute of Nuclear Medicine, Fudan University, Shanghai, 200032, China., Zhang L; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Shanghai Institute of Medical Imaging, Shanghai, 200032, China.; Institute of Nuclear Medicine, Fudan University, Shanghai, 200032, China., Agostini D; Department of Nuclear Medicine, University Hospital of Caen and Normandie Université, Caen, 14000, France., Besson FL; Department of Nuclear Medicine‑Molecular Imaging, AP‑HP, DMU Smart Imaging, Hôpitaux Universitaires Paris‑Saclay, CHU Bicêtre, Paris, 92140, France., Rominger A; Department of Nuclear Medicine, Bern University Hospital, Inselspital, University of Bern, Bern, CH-3010, Switzerland., Al-Ibraheem A; Department of Nuclear Medicine and PET/CT, King Hussein Cancer Center (KHCC), Amman, 11941, Jordan., Zheng J; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Medical Imaging, University of Virginia School of Medicine, Charlottesville, VA, 22908-0170, USA., Nardo L; Department of Radiology, University of California Davis Medical Center, Sacramento, CA, 95817, USA., Li X; Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. li.xuening@zs-hospital.sh.cn., Shi H; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. shi.hongcheng@zs-hospital.sh.cn.; Shanghai Institute of Medical Imaging, Shanghai, 200032, China. shi.hongcheng@zs-hospital.sh.cn.; Institute of Nuclear Medicine, Fudan University, Shanghai, 200032, China. shi.hongcheng@zs-hospital.sh.cn.; Department of Nuclear Medicine, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, 361004, China. shi.hongcheng@zs-hospital.sh.cn.
Source: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2026 Jun 16. Date of Electronic Publication: 2026 Jun 16.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-7089 (Electronic) Linking ISSN: 16197070 NLM ISO Abbreviation: Eur J Nucl Med Mol Imaging Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Detailed pharmacokinetic features of a novel bis-boron <superscript>18</superscript>F-trifluoroborate acid in healthy volunteers: comparable and additional values of total-body PET-imaging-derived analysis.
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  Data: <searchLink fieldCode="AU" term="%22Liu+G%22">Liu G</searchLink>; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Shanghai Institute of Medical Imaging, Shanghai, 200032, China.; Institute of Nuclear Medicine, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Lv+J%22">Lv J</searchLink>; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Shanghai Institute of Medical Imaging, Shanghai, 200032, China.; Institute of Nuclear Medicine, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Xie+Y%22">Xie Y</searchLink>; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Shanghai Institute of Medical Imaging, Shanghai, 200032, China.; Institute of Nuclear Medicine, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Shanghai Institute of Medical Imaging, Shanghai, 200032, China.; Institute of Nuclear Medicine, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Agostini+D%22">Agostini D</searchLink>; Department of Nuclear Medicine, University Hospital of Caen and Normandie Université, Caen, 14000, France.<br /><searchLink fieldCode="AU" term="%22Besson+FL%22">Besson FL</searchLink>; Department of Nuclear Medicine‑Molecular Imaging, AP‑HP, DMU Smart Imaging, Hôpitaux Universitaires Paris‑Saclay, CHU Bicêtre, Paris, 92140, France.<br /><searchLink fieldCode="AU" term="%22Rominger+A%22">Rominger A</searchLink>; Department of Nuclear Medicine, Bern University Hospital, Inselspital, University of Bern, Bern, CH-3010, Switzerland.<br /><searchLink fieldCode="AU" term="%22Al-Ibraheem+A%22">Al-Ibraheem A</searchLink>; Department of Nuclear Medicine and PET/CT, King Hussein Cancer Center (KHCC), Amman, 11941, Jordan.<br /><searchLink fieldCode="AU" term="%22Zheng+J%22">Zheng J</searchLink>; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Medical Imaging, University of Virginia School of Medicine, Charlottesville, VA, 22908-0170, USA.<br /><searchLink fieldCode="AU" term="%22Nardo+L%22">Nardo L</searchLink>; Department of Radiology, University of California Davis Medical Center, Sacramento, CA, 95817, USA.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. li.xuening@zs-hospital.sh.cn.<br /><searchLink fieldCode="AU" term="%22Shi+H%22">Shi H</searchLink>; Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. shi.hongcheng@zs-hospital.sh.cn.; Shanghai Institute of Medical Imaging, Shanghai, 200032, China. shi.hongcheng@zs-hospital.sh.cn.; Institute of Nuclear Medicine, Fudan University, Shanghai, 200032, China. shi.hongcheng@zs-hospital.sh.cn.; Department of Nuclear Medicine, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, 361004, China. shi.hongcheng@zs-hospital.sh.cn.
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        Value: 10.1007/s00259-026-08004-z
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              Text: 2026 Jun 16
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