Structural characterizations of the Mycobacterium tuberculosis AdaA-AlkA (Rv1317c) bifunctional enzyme and identification of enprofylline as a candidate synergistic DNA-repair targeting agent through integrated computational and experimental approaches.
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| Title: | Structural characterizations of the Mycobacterium tuberculosis AdaA-AlkA (Rv1317c) bifunctional enzyme and identification of enprofylline as a candidate synergistic DNA-repair targeting agent through integrated computational and experimental approaches. |
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| Authors: | Sharma R; Department of Molecular Medicine, Jamia Hamdard, New Delhi, 110062, India., Choudhary K; Department of Molecular Medicine, Jamia Hamdard, New Delhi, 110062, India., Mehto NK; Department of Biotechnology, Jamia Hamdard, New Delhi, 110062, India., Grover A; School of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India., Grover S; Department of Molecular Medicine, Jamia Hamdard, New Delhi, 110062, India. Electronic address: sonamgrover@jamiahamdard.ac.in. |
| Source: | Computers in biology and medicine [Comput Biol Med] 2026 Jun 16; Vol. 213, pp. 111808. Date of Electronic Publication: 2026 Jun 16. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 1250250 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0534 (Electronic) Linking ISSN: 00104825 NLM ISO Abbreviation: Comput Biol Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1879-0534 |
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| DOI: | 10.1016/j.compbiomed.2026.111808 |